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ID 16426
Eprint ID
16426
フルテキストURL
Thumnail 96_511.pdf 335 KB
タイトル(別表記)
Study on the role of catalase for uptake of metallic mercury Part 4 In vitro reduction of mercuric ion by superoxide anion, NADPH, NADH and acatalasemic mouse liver homogenate
著者
劒持 堅志 岡山大学医学部公衆衛生学教室
抄録
In vitro reduction of mercuric ion to metallic mercury by superoxide anion, NADPH, NADH and acatalasemic mouse liver homogenate was investigated. Superoxide anion generated by the xanthine-xanthine oxidase system reduced mercuric ion to metallic mercury in vitro. The reduction rate was inceresed linearly by the increasing concentration of xanthine oxidase. The reduction of mercuric ion by superoxide anion was increased by the addition of cytochrome c and nitro blue tetrazolium. The reduction of mercuric ion was inhibited in the presence of superoxide dismutase and catalase. The rate of reduction of mercuric ion by acatalasemic mouse liver homogenates was higher than that by normal mice liver homogenate. The reduction of mercuric ion by mouse liver homogenate was inhibited by the generation of superoxide anion, but the reduction rate by acatalasemic mouse liver homogenate was higher than that of normal mouse homogenate. NADPH and NADH reduced mercuric ion to metallic mercury. The reduction decreased in the presence of mouse liver homogenate. These results indicate that metabolism of mercury is influenced by the balance of oxidation and reduction systems
キーワード
reduction of mercuric ion
superoxide anion
NADPH
NADH
catalase
発行日
1984-04-30
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
96巻
5-6号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
511
終了ページ
517
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/96/5-6/96_5-6_511/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/index.html
言語
Japanese
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma