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ID 15850
Eprint ID
15850
フルテキストURL
Thumnail 100_47.pdf 640 KB
タイトル(別表記)
Studies of lipid metabolism in cultured smooth muscle cells.Part II. Effect of antioxidants on fatty acid metabolism.
著者
出宮 通孝 岡山大学医学部第2内科教室
抄録
The effects of antioxidants on the fatty acid composition of cultured aortic smooth muscle cells obtained from normal, hypercholesterolemic and aged rabbits were studied in vitro. α-Tocopherol and coenzyme Q(10) were used as antioxidants.Cell lipid extracts were separated into cholesterol ester (CE), triglyceride (TG) and phospholipid (PL) fractions by thin layer chromatography. The fractions were analyzed by gas-liquid chromatography for fatty acid composition. Upon addition of α-tocopherol, the proportion of oleate (18:1) increased and that of linoleate (18:2) decreased in the CE and TG fractions, but that of stearate (18:0) increased and those of linoleate and arachidonate (20:4) decreased in the PL fraction.These effects of α-tocopherol were most significant in HL-SMC, and almost no change in Aged-SMC was observed.Addition of coenzyme Q(10) resulted small changes in the fatty acid composition of the cultured cells and culture media.
キーワード
平滑筋細胞
脂肪酸分析
α-トコフェロール
コエンザイムQ(10)
抗酸化剤
発行日
1988
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
100巻
1-2号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
47
終了ページ
55
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/100/1-2/100_1-2_47/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/index.html
言語
Japanese
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma