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ID 19044
Eprint ID
19044
フルテキストURL
Thumnail 70_2205.pdf 10.9 MB
タイトル(別表記)
Hematopoietic Action of Iron, Copper and Cobalt by Rabbit Bone Marrow Tissue Culture in Fluid Medium Part 2 Hematopoietic Actions of Cobalt and Copper
著者
久米田 克哉 岡山大学医学部平木内科教室
抄録
1. Hematopoietic actions of cobalt and copper, either singly or in combination with iron have been studied by means of rabbit bone marrow culture in fluid medium. 2. When various cobalt compounds are added singly, with exception of cobalt chloride, every one of them acts markedly to help erythropoiesis, but Hb content on the contrary often decreases by such addition. Consequently, this hypochrome erythropoiesis seems to be due to lack of iron supply. 3. In the case where ferric gluconate is added in combination with cobalt compounds, Hb increses markedly, especially so when the combination is ferric gluconate and cobalt chloride in proportion of 1:50; suggesting that cobalt greatly assists the induction of iron into the heme nucleus. 4. Due to its toxicity, copper addition either singly or in combination with iron does not help erythropoiesis to any great extent, but when in combination with iron as in the case of cobalt copper helps to increase Hb content. 5. The addition of three metals, iron, copper, and cobalt, does not yield the best result, indicating the necessity of giving a consideration to the toxicity arising out of the amount to added.
発行日
1958-06-30
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
70巻
6号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
2205
終了ページ
2221
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/70/6/70_6_2205/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/
言語
Japanese
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma