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ID 18696
Eprint ID
18696
フルテキストURL
Thumnail 75_1127.pdf 4.68 MB
タイトル(別表記)
Study on the Sex Chromatin in Oral Exfoliated Cells
著者
中谷 昌慶 岡山大学医学部口腔外科教室
抄録
So many studies on the sex chromatin have been made so far in various fields since it was discovered as a nucleolar satellite by Barr and Bertram in 1949, but very little has been described about the sex chromatin in exfoliated cells of oral neoplasms. Thus the author started this investgation of the sex chromatin in oral smears in 60 normal persons (30 males and 30 females), 35 benign tumors (17 males and 18 females), 35 malignant tumors (22 males and 13 females) and 14 sexual anomalies. All smear specimens were stained with Moore and Barr's cresyl echt violet technigue, and a sex chromatin was always located along the inner surface of the nuclear membrane of interphase nuclei. The results obtained were as follows; 1) NORMAL CASES Microscopic examination was made on the sex chromatin in smear specimens taken from buccal, gingival and lingual epithelia of the same individual. Incidence of the sex chromatin in females was on an average 23.5±6.50 per cent in buccal smears, 22.0±5.65 per cent in gingival and 21.6±5.76 per cent in lingual, while that in males was ranging from 0 to 2 per cent in smears taken from each area. Minute examinations of sex chromatin showed that they were noticed in a variety of forms, such as triangular, planoconvex, flat and others, of which triangular form was most commonly seen. The average size of sex chromatin in these epithelial cells was about 1.4 X 1.0 μ. 2) TUMOR CASES There was almost no difference between sex chromatin incidences of tumor and its host tissue, except two cases of benign neoplasam, i. e. fibroma and follicular cyst, in females, whose sex chromatin incidences were 4 and 6 per cent. A relationship between sex chromatin incidence and Broders' classification could not be noticed in cases of carcinoma cells. 3) INTERSEX AND SEXUAL ANOMALIES As the result of investigations of sex chromatin in cases of pseudohermaphrotidism, infantilism, Turner's syndrome and hypospadias, the sex chromatin pattern did not always agree with its genetic sex in the patients associated with sex chromosome aberrations, therefore, it will be desirable to make analysis of sex chromosome in determining the sex in the above mentioned patients.
発行日
1963-12-30
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
75巻
11-12号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
1127
終了ページ
1146
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/75/11-12/75_11-12_1127/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/
言語
Japanese
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma