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ID 15917
Eprint ID
15917
フルテキストURL
Thumnail 100_405.pdf 922 KB
タイトル(別表記)
Studies on lipids and fatty acids in rats with streptozotocin-induced insulin deficiency II. Incorporation of 1-(14)C-sodium acetate into lipids and fatty acids of liver slices and whole blood cells
著者
三宅 寛治 岡山大学医学部第二内科学教室
抄録
In order to study the lipid and fatty acid metabolism in the insulin deficient state, the in vitro incorporation of 1-(14)C-sodium acetate into major lipid fractions and fatty acids of liver slices and whole blood cells was determined. Rats were studied one week, one month and three months after insulin deficiency was induced by administration of streptozotocin.The net incorporation of (14)C into lipid fractions and total fatty acids of liver slices significantly decreased after one week. On the other hand the net incorporation of (14)C into the lipid fractions and total fatty acids of whole blood cells showed a tendency to decrease after three months.The net (14)C incorporation into free cholesterol decreased significantly and that into phospholipids increased significantly in liver slices after one week. The net (14)C incorporation into free cholesterol of whole blood cells decreased significantly on the same day.A significant decrease in the percent incorporation of (14)C into oleic acid was observed in both liver slices and whole blood cells after one month and three months.
キーワード
streptozotocin
肝スライス
全血細胞
(14)Cの取り込み
発行日
1988
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
100巻
3-4号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
405
終了ページ
418
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/100/3-4/100_3-4_405/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/
言語
Japanese
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma