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ID 18667
Eprint ID
18667
フルテキストURL
Thumnail 72_1615.pdf 366 KB
タイトル(別表記)
Effect of High Hydrostatic Pressure on Smooth Muscle Part Ⅱ. Effect of some drugs on the longitudinal muscle of frog intestine
著者
三木 福治郎 岡山大学医学部第一生理学教室
抄録
High hydrostatic pressure (50 to 500 kg/㎠) was applied to isolated longitudinal muscle strip (10 to 15 mm long, 2 to 3 mm wide) of frog intestine immersed in Ringer's solution containing some drugs, and from the observation of changes of the tonus and rhythmical movement of the preparation following results were obtained. 1) When a drug acts upon the strip during compression, such as magnesium sulfate, barium chloride, acetylcholine or atropine sulfate, the changes on the strip result in algebraic summation of the pressure- and drug-effects. But the action of adrenaline chloride on the strip is reversed under high hydrostatic pressure. Namely, the movement of the strip inhibited by adrenaline or pressure respectively, but it is augumented when the pressure is applied on the strip immersed in the adrenaline-Ringer's solution. 2) The stimulative effect on the muscle strip under high hydrostatic pressure up to 100 kg/㎠ is of neurogenic nature. But under pressure from 300 to 500 kg/㎠ the first instaneous lengthening of the strip and successive slow shortening are observed and this effect is of myogenic nature. 3) The temporary contraction of the strip immediately after decompression may be considered as an adaptive process in biological phenomenon.
発行日
1960-10-30
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
72巻
8-10号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
1615
終了ページ
1621
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/72/8-10/72_8-10_1615/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/
言語
Japanese
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma