Published by Misasa Medical Center, Okayama University Medical School
Published by Misasa Medical Center, Okayama University Medical School

<Formerly known as>
岡大三朝分院研究報告 (63号-72号) 環境病態研報告 (57号-62号)
岡山大学温泉研究所報告 (5号-56号) 放射能泉研究所報告 (1号-4号)

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Low attenuation area on computed tomography in asthma. Comparison between smoking and nonsmoking subjects.

谷崎 勝朗 岡山大学医学部附属病院三朝分院内科
光延 文裕 岡山大学医学部附属病院三朝分院内科 Kaken ID researchmap
芦田 耕三 岡山大学医学部附属病院三朝分院内科
御舩 尚志 岡山大学医学部附属病院三朝分院内科
保崎 泰弘 岡山大学医学部附属病院三朝分院内科
柘野 浩史 岡山大学医学部附属病院三朝分院内科
岡本 誠 岡山大学医学部附属病院三朝分院内科
岩垣 尚志 岡山大学医学部附属病院三朝分院内科
山本 和彦 岡山大学医学部附属病院三朝分院内科
中井 睦郎 岡山大学医学部附属病院三朝分院放射線室
穐山 恒雄 岡山大学医学部附属病院三朝分院放射線室
The percentage of attenuation area < -950HU (% LAA) on high resolution computed tomography (HRCT) was compared between 17 smoking and 24 nonsmoking patients with asthma. 1. FEV1/FVC value was lower in smoking patients (56.4%) than in nonsmoking patients (66.0%), however, the difference was not significant. 2. The percentage of LAA of the lung was larger in smoking patients compared with that in nonsmoking patients in all the three anatomic levels: the % LAA was 14.4% in nonsmoking and 20.3% in smoking patients at lower lung level (3cm above the top of the diaphragm). However, this was not significant. The maximal % LAA among the three lung levels on HRCT was 21.6±12.5% in smoking, and 15.7±11.9% in nonsmoking patients. This suggested that the maximal % LAA was larger in smoking patients, however, this was not significant. 3. The mean CT number of the lung on HRCT was smaller in smoking patients (-897.3HU) than in nonsmoking patients (-884.7HU). 4. Three of 4 nonsmoking patients whose % LAA was more than 30% had severe intractable asthma with long-term glucocorticoid therapy. The results suggest the possibility that smoking influences the % LAA of the lung on HRCT in asthma. It could be also speculated that % LAA is influenced by severity of asthma.
bronchial asthma
mean CT number