Journal of Okayama Medical Association
Published by Okayama Medical Association

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Trichloroethane中毒に関する実験的研究 第2編 1,1,1-或は1 1 2-trichloroethane 投与後の呼気および尿への排泄

高原 和夫 岡山大学医学部公衆衛生学教室
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抄録
Mice were injected intraperitoneally with 1, 1, 1-and 1, 1, 2-trichloroethane (TCE), and the amounts of their metabolites exhaled from the lungs and excreted in the urine were measured. Exhalation from the lungs ended 7 hours after the injection. The ratio of the accumulated amount of 1, 1, 1-TCE to the amount of 1, 1, 1-TCE injected was 84.7% , and the ratio for 1, 1, 2-TCE was 9.8% . The accumulated amount of total trichloro-compounds in the urine of mice to the amount of 1, 1, 1-TCE injected was 1.07% , and that for 1, 1, 2-TCE was 0.15% . The total amount exhaled from the lungs and that excreted in the urine of mice injected with 1, 1, 1-TCE was greater than that of mice injected with 1, 1, 2-TCE.
キーワード
1,1,1-トリクロロエタン
1,1,2-トリクロロエタン
呼気排泄
尿排泄
尿中代謝産物
ISSN
0030-1558
NCID
AN00032489