Acute renal failure (ARF) is a syndrome in which rapid loss of renal function and parenchymal damage progress to uremia. The causes of ARF are so many and varied that no established theory exists concerning the factors of symptom development and their antecedents. The author made a histopathological study of kidney tissue from 12 patients with ARF due to ischemia, 8 with DIC and 4 without, and examined the relationship between pathological changes in the tissue and pathogenesis. The morbidity, pathology and prognosis of the patients were also examined. The degree of DIC was found to influence ARF symptom development and the recovery of renal function. It was concluded that histological examination of biopsy specimens was effective in determining the prognosis and establishing therapeutic guidelines.
Acute Renal Failure
Disseminated Intravascular Coagulation