Journal of Okayama Medical Association
Published by Okayama Medical Association

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黄色ブドウ球菌カロチノイド色素の分析化学的検討と生理的意義について

篠井 加津子 岡山大学医学部細菌学教室
Thumnail 92_73.pdf 546 KB
抄録
Although carotenoid is one of the typical pigments in Staphylococcus aureus, its properties and physiological role have not been well characterized. This paper examined carotenoid of S. aureus in regard to (1) factors affecting its production. (2) chemical properties and (3) its effect on liposomal permeability. (1) Carotenoid content increased during the late logarithmic growth phase. Production was potently accelerated by the addition of 10% NaCl (10 fold), 2% glycerin (10 fold) and 1% glycerolmonoacetate (250 fold). Oxygen was necessary but visible light did not effect the production. (2) The major component of carotenoid was C(30)Diaponeurosporenoic acid methyl ester. Minor components were Diaponeurosporene, Diapo-∫-carotene, Diapolycopenoic acid methyl ester, Diaponeurosporene ester and a hydroxyl derivative of Diaponeurosporene. Staphylococcal carotenoids were all C(30). (3) The addition of carotenoid to liposomes (made of staphylococcal phospholipids) increased the permeability for glycerol and glucose. This indicates that production of carotenoid may be an adaptational response of the bacteria.
キーワード
黄色ブドウ球菌
カロチノイド色素分析
Neurosporenoic acid
ISSN
0030-1558
NCID
AN00032489