Journal of Okayama Medical Association
Published by Okayama Medical Association

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Full-text articles are available 3 years after publication.

亜硝酸イオンと硝酸イオンのミトコンドリア膜に対する作用について

井上 堅太郎 岡山大学医学部公衆衛生学教室
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抄録
Effects of NaNO(2) and NaNO(3) on the oxidative phosphorylation of mitochondria were studied, and following results were obtained. 1) The effect of NaNO(2) on the oxidative phosphorylation is higher than NaNO(3). 2) Relative activity of State 4 is activated by NaNO(2) (1-10mM) added to reaction mixture. 3) The respiratory control index of mitochondria is decreased by NaNO(2). 4) The effect of NO(2) on oxidative phosphorylation in the borate buffer as reaction mixture is higher than that in the tris-HCL buffer. It is suggested that NO(2) has a probability of the reaction on -NH(2) site of mitochondria.
ISSN
0030-1558
NCID
AN00032489