Journal of Okayama Medical Association
Published by Okayama Medical Association

Full-text articles are available 3 years after publication.

乳腺腫瘍におけるEstrogen binding proteinに関する研究 第Ⅰ編 特にEstrogen binding proteinの分析について

鶴野 正基 岡山大学医学部第一外科教室
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Estrogen binding protein (EBP) in mammary tumor was studied in DMBA induced rat mammary carcinoma, Shionogi carcinoma 115, Shionogi carcinoma 42 and human mammary tumor by use of (3)H-estradiol. Free and bound estradiol was separated by Sephadex G-25. Specific EBP was calculated 4.5S by sucrose gradient centrifugation. Non-specific EBP was observed in the 3.2S-3.6S region of the ultracentrifugal analysis. Specific EBP was migrated to anodic region of α- or β-position in disc electrophoresis.