Journal of Okayama Medical Association
Published by Okayama Medical Association

Full-text articles are available 3 years after publication.

Bleomycinの造血器に及ぼす影響に関する研究 第1編 Bleomycinの正常家兎骨髄白血球系造血に対する影響について

国政 郁哉 岡山大学医学部平木内科教室
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In order to observe the influence of Bleomycin on the bone marrow leukopoiesis, clinical Tissue culture of bone marrow from normal rabbits was conducted. Bleomycin solution at various concentrations were added directly to the culture media and observations were carried out on the outgrowth, cell density, wandering velosity of pseudoeosinophils, carbon particle phagocytosis. The experimental results demonstrate that the leukopoietic functions of bone marrow were not inhibited in the medium containning 0.0005mg/ml, 0.05mg/ml and 5mg/ml of Bleomycin.