Journal of Okayama Medical Association
Published by Okayama Medical Association

Full-text articles are available 3 years after publication.

移植動物癌腫瘍抗原に関する研究 第2編 Ehrlich腹水癌腫瘍リボゾーム蛋白の抗原性について

只友 康雄 岡山大学医学部第1(田中)外科教室
80_691.pdf 2.12 MB
Antigenicity of ribosomal protein in Ehrlich ascites tumor and the biochemical characters were studied. The cytotoxic activity of immunized male dd-mice serum globulin was proved by cell culture test. Ribosomal protein was moved electrophoretically to basic side than that of serum γ-globulin, and the protein concentraticn was adequate for maximal antigenicity 1 mg per mouse. The antitumor activity of immunized εerum globulin was most elevated at 25 th day after immunization, and that of lymph nodes and spleen were at 10 th day. The antitumor activity of immunized serum globulin was mainly existed in γ-globulin fraction, but also contained in α-and β-globulin fraction.