Lipoathledin is the fatty acid fractions extracted from x-ray irradiated rabit organs. We applicated 2% Lipoathledin absorption ointment to the superficial fungal infections clinically and following results were obtained. 1) Lipoathledin has obvious antifungal effect. 2) 56 in 67 patients of superficial fungal infections (83.6%) were improved clinically. 3) No significant side effects were observed.