Journal of Okayama Medical Association
Published by Okayama Medical Association

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肝炎並びに肝硬変症に於ける指爪根部微細小血管に関する研究 第2編 二,三薬物の指爪根部微細小血管に及ぼす影響

前〓 忠義 岡山大学医学部第一内科教室
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抄録
The studies were made on the effects of Greenpole on the capillary picture at the root of the nail in the cases of acute and chronic infectious hepatitis as well as cirrhosis of the liver, in comparison with the toxins for vegetative nerves. And the following results were obtained. 1. Following the administration of Greenpole, the contractions of the arterial feet of the capillaries were observed mainly in the acute hepatitis cases, on the other hand, the contractions of the venous feet in the chronic hepatitis and liver-cirrhosis cases were seen. Following the administration of Greenpole, accelated blood flow was noted in 60% of acute hepatitis, 50% of chronic hepatitis and in 100% of cirrho is, and the formation of granules, seen in 7 cases, had all disappeared. 2. The disappearance of the granules following the administration of Greenpole, was appeared presumably due to washing away clumps of the blood in the microaneurysms.3. The contractions of the arterial feet of the capillaries began 5 minutes after the administration of Greenpole, maximum after 40 minutes and kept up fairly strong contractions for 50 minutes. The contractions of the venous ones began from 5 minutes after and maximum at 20 minutes. 4. Following the administration of adrenalin, it was observed in the cases of chronic hepatitis that the contractions of the arterial feet of the capillaries were noted in 60%, of the venous ones in 66.7% and of the capillary loops in 33.3 to 40%. Maximum contractions were observed in 79.0% after 5 minutes. On the other hand, the contractions of the venous feet were fairly strong after 5 minutes and were maximum after 10 minutes in the rate of 79.5%. However, the granules had not disappeared following the administration of adrenalin.5. In consequence, the effects of Greenpole were thought to be essentially different from adrenalin although some similarities were observed.6. No clinical improvement was noted in the cases of chronic hepatitis after the administration of pilocarpin and atropin.
ISSN
0030-1558
NCID
AN00032489