After the administration of serum and thyroid-extract from the patient of the thyroid disease, the weight, the uptake of Radioiodine and iodization in the rat thyroid gland were studied.
The results obtained are as follows: 1) There were no influence to the rat thyroid by the administration of patient's serum. 2) The administration of thyroid extract caused the decrease of rat body weight, I(131) uptake and thyroxine fraction in the thyroid gland. It seems that thyroid extract has the same action with the thyroid substance and is more effective.