Journal of Okayama Medical Association
Published by Okayama Medical Association

Full-text articles are available 3 years after publication.

輸血の副作用時における血清核酸量およびカルシウム量の変動とその抑制に関する研究 第2編 同種不適合異型輸血・異種属輸血時における血清核酸量およびカルシウム量の変動とその抑制に関する実験的研究

佐藤 弘充 岡山大学医学部第1(陣内)外科教室
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In the cases of inadequate heterotrasfusion with 13~15cc. of blood per kg every rabbit showed marked hypolention and 2 cases died in 5 cases. And the serum calium content was decreased, the surum mucleic acid content, both RNA and DNA, was increased by the shock. These ill effects were restrained by Ravonal, Anergen and Contomin. From the above mentioned facts it is considered that, the inhibition of Ravonal, Anergen and Contomin to ill effects of inspecific or inadequate heterotransfusion is primarily not due to their inhibiting action to the hemolysis, but to that to the shock of hemolytic toxin, by depresing organ-metabolism hemolysis itself, but to the shock of hemolytic toxin by the descending of organ-metabolism.