Journal of Okayama Medical Association
Published by Okayama Medical Association

Full-text articles are available 3 years after publication.

枸櫞酸中毒症の実験的研究 第2編 枸櫞酸中毒と出血性傾向並びに肝機能

伊達 和 岡山大学医学部第二外科教室
Thumnail 71_457.pdf 534 KB
Experiment of citrate infusion was performed on dogs, and obtained following results. 1) Serum calcium and calcium-ion were increased, probably becaus of release of tissue calcium into blood. 2) Bleeding time was slightly prolonged, but clotting time was rather reduced. 3) Platelets count tended to be increased. 4) Prothrombin concentration was slightly decreased but no fibrinolysis was observed in all cases. No significant changes were observed in fibrinogen, recalcification time, thrombin time and prothrombin conversion time. 5) Liver function tests (B. S. P., and protein metabolism test) showed slight disorder in liver function. 6) From the facts above, it was concluded that infusion of citrate has not resulted in hemorrhagic tendency.