Journal of Okayama Medical Association
Published by Okayama Medical Association

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Full-text articles are available 3 years after publication.

鉤虫症の鉄代謝に関する研究 第2編 鉤虫症血清注射時及び各種実験的貧血に於ける臓器非ヘミン鉄量

中塚 銀太 岡山大学医学部平木内科教室
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抄録
By studying the effect of hookworm disease serum injection on the iron metabolism in rabbits given such injections and. comparing the same in experimental anemia, the following conclusions have been drawn. 1. In the rabbits given injection of hookworm disease serum, serum iron shows a decrease, while non-hemin iron content in the viscera tends to show an increase in each fraction (4 non-hemin iron fractions of Yoneyama and Konno's method). 2. The results differ from those in phenylhydrazine anemia, collargol anemia and roentgen anemia; and consequently hemolysis, of course, and also a transient disturbance in bone marrow can not be considered as the causative factors of hookworm anemia. 3. From these findings there seems to exist a factor in serum, which inhibits iron mobilization, thus bringing about iron deficiency in the erythropoietic system in bone marrow; and this seems to constitute an important causative factor for the anemia in this disease.
ISSN
0030-1558
NCID
AN00032489