Journal of Okayama Medical Association
Published by Okayama Medical Association

Full-text articles are available 3 years after publication.

感光色素の微生物に対する影響に就いて 第1編 感光色素の抗菌性に就いて

大石 正男 岡山大学医学部微生物学教室
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The author studied the antimicrobial activity of photosensitizing dyes as food preservatives, and obtained the following results: 1) Antimicrobial activities of photosensitizing dyes to various sorts of microorganisms are in parallel with each other. 2) The following are the photosensitizing dyes which showed a relatively high antimicrobial activity to all the tested organisms: four kinds of monomethine cyanine, NK 266 (4.4'-dimethyl-3.3'-dihepthyl-2.2'-monomethine thiazolocyanine-3-iodide), NK 400 (4.4'-dimethyl-3.3'-diocthyl-2.2'-monomethine thiazolocyanine-3-iodide), NK 564 (4.4'-dimethyl-3.3'-dihepthyl-2.2'-monomethine thiazolocyanine-3-chloride), NK 570 (4.4'-dimethyl-3.3'-diocthyl-2.2'-monomethine thiazolocyanine-3-acetate); a kind of mesochlor pentamethine cyanine, NK 74 (3.3'-diethyl-10-chlor-2.2'-pentamethine thiocyanine-3-iodide); a kind of styryl type dye, NK 573 (2.6. bis (p-dimethylaminostyryl) pyridine-1-methylacetate). 3) Many photesensitizing dyes were proved to be of use as food preservatives. For the practical use, however, further tests on the toxicity and trial application to foods are necessary.