Journal of Okayama Medical Association
Published by Okayama Medical Association

Full-text articles are available 3 years after publication.

Diamoxの抗痙攣効果に関する研究 第3編 Diamoxの脳髄Cholinesterase活性値に及ぼす影響

河原 佳正 岡山大学医学部第1(陣内)外科教室
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The effects of Diamox on the cholinesterase activities in nucleus lenticularis of cats brain were measured. The experiments were performed by Ammon method taking the sanples at 9 and 24 hours respectively after the injection of Diamox. Concerning about the mean values of each 7 cases, the cholinesterase activities showed 44.8% increase at 9 hours and 43.4% increase at 24 hours. The anticonvulsive effects of Diamox were considered to be caused by the acceleration of the acetylcholin decomposition of cholinesterase from these experimental results.