Journal of Okayama Medical Association
Published by Okayama Medical Association

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Full-text articles are available 3 years after publication.

Formalinに依る抗原変性,殊に反応強化に就て

大塚 信夫 岡山大学医学部衛生学教室
Thumnail 69_1025.pdf 426 KB
抄録
Activity of antigen were studied after different concentrations of formalin was added to antigen for various period of time. Experiments were performed with precipitin reactions, complement fixation tests, and anaphylaxis. Following results were obtained. There were found exaggerated reactions with increase of period during which time antigen was exposed to formalin. Activity of antigen was reduced when concentrated formalin was used as experimental reagent, while increase of activity was noticed in the case of diluted formalin. A peak of activity of antigen was found when 0.001 per-cent formalin had been reacted to antigen at 37°C for 24 hours.
ISSN
0030-1558
NCID
AN00032489