Journal of Okayama Medical Association
Published by Okayama Medical Association

Full-text articles are available 3 years after publication.

岡山県下に発生した流行性肝炎 特にその病原体に関する研究 第1編 分離病毒の一般性状,特に熱に対する抵抗性に就て

時末 聰 岡山大学医学部微生物学教室
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By the cultivation in fertile hen's eggs, a kind of virus which could be regarded as the agent of hepatitis was isolated from the hepatitis patients in Okayama Prefectur. Under various conditions, the author carried out the experiments to study the heat-resistance of the isolated virus. The estblishment of infection was judged by the pathological changes of inoculated mouse liver. The results were as follows: 1) The isolated virus was highly resistant to heat, but was inactivated by heating at 75°C for 30 minutes. This was a very characteristic nature of the isolated virus to differentiate it from other simillar viruses. 2) In respect to the nature of heat-resistance, this virus was inferred to be very similar to the one described by Havens in his human body experiment.