The author has done comparative studies on the resectable limit and regeneration of the remaining liver between the liver with localized injury, which was functionally compensated, and the normal liver, after performing two stage hepatectomy. Adult dogs were used for the studies and the values were calculated by a presumptive method. (1) The resectable limit on the normal liver was 77.9%. (2) The regencrated liver after resection of the normal liver mostly reduced the weight less than 15% compared to that of the original liver. (3) There were almost no differences in the resectable limits between the liver with localized injury and the normal liver. (4) Regeneration of the liver after resection of the liver with localized injury lowered nearly 10% compared to that of the normal liver.