Journal of Okayama Medical Association
Published by Okayama Medical Association

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On the action of some drugs upon the arterioles and capillaries

岡田 正矩 Physiological Department of University Okayama
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抄録
1. Direct application of the mustard-oil to the web, mesentery and bladder wall of frog, caused remarkable dilatation both on the arterioles and capillaries. And capillaries are dilated independently of variation in the arterial blood pressure. 2. A solution of guanidin stronger than 5.0 p. c. has constricting effect upon the arterioles and capillaries, while weak solution (1.0-4.0 p. c.) causes dilatation of the arterioles and capillaries. 3. Adrenalin has contractive effect upon the arterioles but it shows, on the other hand, dilatation of capillaries indepent of variation in the arterial blood pressure. 4. Pituitrin causes contraction of the arterioles, on the contrary, capillaries are always dilated. Its contractive (upon the arterioles) and dilator effect (upon the capillaries) are weaker than that produced with adrenalin. 5. Caffein shows dilator effect both on the arterioles and capillaries. The dilatation of capillaries is independent of variation in the arterial blood pressure. 6. Isotonic solution (with 0.65 p. c. NaCL) of NaNo3, NaNO2 and Na2HPO4 causes slight dilatation of the arterioles and capillaries, while kalium salts (t. i. KCLO, KNO3, KBr etc.) contraction. Calcium salts and magnecium salts have dilator effect both on the arterioles and capillaries. Some organic substances which have reducing ability, have dilator effect upon the arterioles and capillaries.
備考
原著
ISSN
0030-1558
NCID
AN00032489