Journal of Okayama Medical Association
Published by Okayama Medical Association

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Rituximab併用CHOP療法が奏効した肝原発びまん性大細胞型B細胞リンパ腫の1例

岡田 博 岡山赤十字病院
藤井 総一郎 岡山赤十字病院
渡邉 謙太郎 岡山赤十字病院
重松 照伸 岡山赤十字病院
宮下 雄博 岡山赤十字病院
岡崎 守宏 岡山赤十字病院
小橋 春彦 岡山赤十字病院
横山 元浩 岡山赤十字病院
吉野 正 岡山大学大学院医歯薬学総合研究科
Thumnail 127_209.pdf 10.4 MB
抄録
 A 78-year-old Japanese man was referred to our hospital after experiencing black feces. No abnormal finding was detected in the endoscopic examination of his stomach and large intestines. Computed tomography (CT) of the abdomen revealed a tumor lesion in the right lobe of the liver. A needle biopsy of the tumor under ultrasound guidance was performed. A pathological examination of the biopsy specimen showed a diffuse proliferation of lymphoma cells, which was compatible with diffuse large B-cell lymphoma (DLBCL). F-fluorodeoxyglucose (FDG)-positron emission tomography (PET)-CT demonstrated increased FDG uptake only in the liver tumor. We made the diagnosis of primary DLBCL of the liver. After six cycles of rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisolone (R-CHOP), the patient achieved complete remission and has maintained remission for 2 years since the diagnosis. The R-CHOP regimen might be effective therapy for primary DLBCL of the liver.
キーワード
びまん性大細胞型B細胞リンパ腫(diffuse large B-cell lymphoma)
肝臓(liver)
R-CHOP療法(R-CHOP regimen)
備考
症例報告(Case Reports)
ISSN
0030-1558
NCID
AN00032489
DOI
NAID