Journal of Okayama Medical Association
Published by Okayama Medical Association

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Full-text articles are available 3 years after publication.

術前DCF療法が著効した食道原発内分泌細胞癌の1切除例

前田 直見 岡山大学病院 消化管外科
白川 靖博 岡山大学病院 消化管外科
國府島 健 岡山大学病院 消化管外科
大原 利章 岡山大学病院 消化管外科
田邊 俊輔 岡山大学病院 消化管外科
野間 和広 岡山大学病院 消化管外科
櫻間 教文 岡山大学病院 消化管外科
藤原 俊義 岡山大学病院 消化管外科
Thumnail 126_39.pdf 3.34 MB
抄録
 Esophageal endocrine cell carcinoma is extremely rare. We report a case of esophageal endocrine cell carcinoma showing histological complete response to neoadjuvant chemotherapy with docetaxel/cisplatin/5-fluorouracil (DCF). A 66-year-old man had been experiencing epigastralgia, and a type 2 tumor in the thoracic part of esophagus was detected by upper endoscopy. The biopsy showed endocrine cell carcinoma. PET/CT, endoscopy and an esophagogram showed that the patient had a 70-mm scaled type 2 tumor in the middle thoracic esophagus, and they also revealed lymph node metastases (no. 106recR). We diagnosed a cT3cN1cM0 cStage III tumor. With two courses of DCF treatment, both the primary tumor and lymph node metastases showed a partial response. We performed a subtotal esophagectomy with three-field lymph node dissection. The pathological examination of the resected specimens revealed no malignant cells in the esophagus or lymph nodes, and we concluded that the pathological effect of the DCF treatment was Grade 3.
キーワード
食道癌(esophageal cancer)
内分泌細胞癌(endocrine cell carcinoma)
DCF療法(DCF treatment)
備考
症例報告 (Case Reports)
ISSN
0030-1558
NCID
AN00032489
DOI