Journal of Okayama Medical Association
Published by Okayama Medical Association

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Full-text articles are available 3 years after publication.

肝動脈塞栓術施行或は非施行ヒト肝癌組織の初代培養と株化

日下 泰徳 岡山大学医学部癌源研究施設病理部門
常盤 孝義 岡山大学医学部癌源研究施設病理部門
佐藤 二郎 岡山大学医学部癌源研究施設病理部門
津下 宏 岡山大学医学部第一外科学教室
浜崎 啓介 岡山大学医学部第一外科学教室
三村 久 岡山大学医学部第一外科学教室
折田 薫三 岡山大学医学部第一外科学教室
Thumnail 101_131.pdf 2.71 MB
抄録
Primary culture of human primary liver cancer tissues treated with or without trancatheter arterial embolization (TAE) was perfomed with the following results. 1. The yield and viability were very low in cells from primary liver cancer tissues dissociated with enzymes. 2. Epithelial-like cells were found from TAE-treated cancer tissues at a ratio of 1/8 in both monolayer and explant culture and from TAE-nontreated tissues at a ratio of 4/12 in monolayer culture and 3/12 in explant culture. The AFP-producing capahity of these epithelial-like cells has been maintained from one week to one month in culture. 3. Cells derived from two TAE-nontreated cancer tissues were subculturable. One was established as a cholangiocellular carcinoma cell line. 4. No heterotransplantability of primary cultured cancer cells into nude mice was found.
キーワード
TAE
ヒト肝癌
初代培養
株化
ISSN
0030-1558
NCID
AN00032489