Journal of Okayama Medical Association
Published by Okayama Medical Association

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Full-text articles are available 3 years after publication.

Streptozotocinによるインスリン欠乏ラットにおける脂質ならびに脂肪酸に関する研究 第1編 肝,心,肺,大動脈,脂肪組織,血清の脂質と各脂肪酸量について

三宅 寛治 岡山大学医学部第二内科学教室
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抄録
The lipid and fatty acid metabolism of tissues and plasma of rats was studied one week and three months after insulin deficiency was induced in the rats by treatment with strept-ozotocin. The fatty acid content was analyzed by microcapillary column gas-liquid chromatography. In the liver, significant decreases in triglyceride, cholesterol and phospholipids were observed after one week, and significant decreases in triglyceride were observed after three months. No changes were observed in the heart. In the lung, remarkable decreases in triglyceride and phospholipids were observed after three months. Significant decreases in arachidonic acid were observed in the liver, heart and lung. Significant decreases in palmitic acid were observed in the lung and adipose tissue.
キーワード
streptozotocin
インスリン欠乏ラット
脂質
脂肪酸量
ISSN
0030-1558
NCID
AN00032489