Bulletin of Faculty of Health Sciences Okayama University Medical School
Published by Faculty of Health Sciences Okayama University Medical School

<Formerly known as>
岡山大学医療技術短期大学部紀要 (1巻-9巻)

酵素標識抗体法による人血清中IgM, IgA, IgGリウマチ因子の測定値について

唐下 博子 岡山大学医療技術短期大学部衛生技術学科
一村 光子 岡山大学医療技術短期大学部衛生技術学科
崎山 順子 岡山大学医療技術短期大学部衛生技術学科
大井 治昭 岡山大学医療技術短期大学部衛生技術学科
笹井 誠二 岡山中央血液検査センター
抄録
The measurement of Rheumatoid Factor (RF) has been a valuable tool in diagnosing Rheumatoid Arthritis (RA) for many years. Since Waaler's discovery of the RF, many studies have been carried out. In the recent years studies have been shown that there is no such correlation between the level of the RF titers and disease activity. In this report we have measured the IgM-RF, IgA-RF and IgG-RF by an Enzyme linked immunosorbent assay (ELISA) for 144 normal human sera and 50 patients sera. At the same time we have measured the titers of gelatin particle agglutination (RAPA) and the Latex agglutination (RA-test). The value of IgG-RF have been most correlated to the titers of RAPA (r=0.9037). Using this ELISA technic to detect IgM-, IgA- and IgG-RF, have been aviable more clearly the activity and the stage of Rheumatoid disease.
キーワード
ELISA
IgM-RF
IgA-RF
IgG-RF
RA test
ISSN
0917-4494
NCID
AN10355371