Acta Medica Okayama 71巻 6号
2017-12 発行

Disseminated Nontuberculous Mycobacterial Infection in a Patient with Anti-IFN-γ Autoantibodies

Tanimizu, Masakuni Department of Internal Medicine, Tottori Municipal Hospital
Mizuno, Kenji Department of Surgery, Tottori Municipal Hospital
Hashimoto, Masayuki Department of Radiology, Tottori Municipal Hospital
Publication Date
2017-12
Abstract
We treated a 72-year-old Japanese female with sustained high fever and overall body exhaustion. An infectious liver cyst and right lung pneumonia were suspected causes. Hepatic cystectomy and various antibiotics did not resolve symptoms. Pneumonia exacerbation and ascitic fluid retention, left lumbar spinal osteomyelitis, and peri-gastric lymph node abscess penetrating the stomach were observed. Mycobacterium avium was identified in sputum, ascites, vertebral body abscess puncture specimen, and pus mucus secretion in the stomach. We diagnosed a disseminated nontuberculous mycobacterial infection. She seemed immunocompetent, without signs of AIDS or hematological malignancy. Serum anti-IFN-γ autoantibodies tested positive and were suspected to be involved in the illness onset.
Document Type
Case Report
Keywords
disseminated nontuberculous mycobacterial infection
anti-IFN-γ autoantibodies
Link to PubMed
Thumnail 71_6_547.pdf 3.81 MB