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ID 42586
フルテキストURL
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タイトル(別表記)
Studies on the Pathogenic Agent of Infectious Hepatitis in Okayama Prefecture Chronic infection in the mouse
著者
倉内 嘉人 岡山大学医学部微生物学教室
抄録
The chronic infection was established in the mouse by the inoculation of the virus isolated from the patients of infectious hepatitis in Okayama prefecture, and the infectious course was investigated pathohistologically for about 500 days. The results are summerized as follows; 1) Though most of the mice inoculated with the virus did not succumb but took a chronic course, the typical pathological findings were observed with the liver as the focus. With the laps of time, however, some of the mice died, in which the pathological changes were particularly marked. 2) The general pathological findings were the degeneration and necrosis of the parenchymal cells and the cell infiltration in the liver. These findings varied with the laps of time and the cell infiltration became marked enough to be a sign of infection, though the degeneration and necrosis were still somewhat obserbed. 3) In the lung, there were observed the interalveolitis or the proliferation of round cell or mesenchymal cell around bronchi and blood versels, which was considered to be caused by the infection of the virus. 4) The reversion of the virus from the mouse to chick-embryo was established. This fact suggests that the virus stays in the organs of the infected mouse for a long time and its multiplication and diminution are being repeated.
発行日
1957-07-31
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
69巻
7号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
1653
終了ページ
1667
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/69/7/69_7_1653/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/
言語
Japanese
著作権者
Copyright© 岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma