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ID 40824
フルテキストURL
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タイトル(別表記)
Experimental Study on the Pituitary Adrenal Axis and the Gastric Secretion Part I. The Influence of Adrenocortical Hormone and Adrenocortioctropin on the Gastric Secretion
著者
石田 哲哉 岡山大学医学部第二外科教室
抄録
1) The gastric secretion following the administration of adrenocortical hormones and adrenocorticotropin (ACTH) was examined by the pylorus-ligated rats. 2) The duration of tho pyloric ligature was limited within ten hours, during which the Shay ulcer was commonly not formed and relatively pure gastric juice used to be acquired. 3) The administration of cortisone, pednisolone or desoxycorticosterone depressed the hydrochloric acid secretion, and the degree of decrease was proportional to the administration days (i.e. 1 to 46 days) and dosage (1 to 10 mg) of the hormone. But the continuous administration of 0.5 mg cortisone increased slightly the gastric secretion. 4) ACTH, which was administered subcutaneously 1 to 5 I.U. daily, stimulated highly the production of hydrochloric acid. 5) The dosage of adrenocortical hormone and the decrease in weight of adrenal glands were proportional. The atrophy of adrenals seemed to correspond to the hypacidity. This result indicates that the humoral stimulating mechanism for the gastric secretion by way of the pituitary adrenal axis is present.
発行日
1959-03-25
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
71巻
4-1号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
1501
終了ページ
1510
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/71/4-1/71_4-1_1501/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/
言語
Japanese
OAI-PMH Set
岡山大学
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Sort Key
33
Eprints Journal Name
joma