ID 32218
JaLCDOI
フルテキストURL
著者
Matsuo, Shinji Okayama University
Neya, Toshiaki Okayama University
Yamasato, Teruhiro Okayama University
抄録

Antroduodenal contractions were studied in rat preparations. Augmented duodenal contractions occurred spontaneously in coordination with antral contractions in normal and saline-pretreated preparations. The coordination did not occur when muscle layers and the myenteric plexus were transversely cut at the duodenum just anal to the gastroduodenal junction. In silent preparations, the coordinated contractions were produced by neostigmine or domperidone. When the antroduodenal junctional zone was pretreated with benzalkonium chloride, the augmented duodenal contractions did not occur spontaneously, and even after administration of neostigmine and domperidone although antral contractions occurred spontaneously. In these preparations, there were notably few myenteric neurons in the junctional zone, but the neurons were distributed normally in the areas where motility was recorded. The results suggest that myenteric neurons mediate antroduodenal coordinated contractions and that the coordination is modified by myenteric cholinergic excitatory and dopaminergic inhibitory pathways.

キーワード
gastroduodenal motility
coordinated contraction
myenteric plexus
rat
Amo Type
Article
発行日
1991-02
出版物タイトル
Acta Medica Okayama
45巻
1号
出版者
Okayama University Medical School
開始ページ
21
終了ページ
27
ISSN
0386-300X
NCID
AA00508441
資料タイプ
学術雑誌論文
言語
English
OAI-PMH Set
岡山大学
論文のバージョン
publisher
査読
有り
Submission Path
amo/vol45/iss1/3
PubMed ID
Web of Sience KeyUT
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