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ID 19040
Eprint ID
19040
フルテキストURL
71_239.pdf 2.49 MB
タイトル(別表記)
Experimental Study on the Capillary Permeable Substance in Cancer Toxin
著者
平賀 隆 岡山大学医学部津田外科教室
抄録
The author has studied on the Capillary Permeability Promoting (C. P. P.) Action of cancer toxin and its genesis, obtaining following results. 1) Cancer extract, toxohormone and urine extract of cancer patients have C. P. P. action. 2) A capillary permeable substance, which is heat-resisting and diffusive, is extracted from cancer tissue. This substance has a notable difference in sampling as compared with the capillary permeability of toxohormone and urine extract of cancer patients, and is contained in the globulin fraction on ammonium sulfate method. The substance is found to belong in the polypeptides group according to the results obtained above and to proteineand amino acid tests. 3) In the serum of rabbit administered cancer toxin C. P. P. action and fibrinolysis are observed, and these two actions are significantly interrelated in sampling 4) The C. P. P. action and fibrinolysis produced by administration of cancer toxin are thought to be derived from activation of profibrinolysin to fibrinolysin followed by appearance of permeability of cappillaries. 5) On the study of C. P. P. substance in cancer tissue, used radioactive isotope P(32) as a tracer, function of reticuloendothelial cells is declined and that of mesenchymal cells is accelerated. From the expermental results described above, the action of C. P. P. substance in cancer tissue is considered to play an important role on the growth of cancer and occurrence of cachexia, on thinking the fibrinolysis and the functional decline of cells of the reticuloendothelial system.
発行日
1959-01-31
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
71巻
1号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
239
終了ページ
258
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/71/1/71_1_239/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/
言語
Japanese
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma