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ID 18243
Eprint ID
18243
フルテキストURL
Thumnail 76_91.pdf 828 KB
タイトル(別表記)
Studies on Leukemogenesis in RF Mice by Oral Administration of 20-methylcholanthrene. I. Co-leukemogenic Action of Croton Oil in the Induction of Leukemia by Oral Administration of 20-methylcholanthrene
著者
康 逸雄 岡山大学大学院医学研究科
抄録
1) Myelogenous and lymphocytic leukemias were observed among mice given orally three times a week 0.1-0.15cc of 0.8% 20-methylcholanthrene in olive oil by means of a needle catheter and concurrently painted in the back two times a week with 5% croton oil in benzene. 2) The incident of leukemias was 61.6% for myelogenous and 5.5% for lymphocytic leukemia with a total of 66.6%. On the other hand, mice receiving croton oil alone developed no leukemia. 3) Concurrent administration of 20-methylcholanthrene and croton oil reduced the average latent period required for the development of leukemia by about four weeks in comparison with that of 20-methylcholanthrene treatment alone. 4) From these results, it is concluded that croton oil is coleukemogenic, acting as a promoter in the 20-methylcholanthrene leukemogenesis in mice.
発行日
1964-03-30
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
76巻
1-3号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
91
終了ページ
103
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/76/1-3/76_1-3_91/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/
言語
Japanese
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma