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ID 17664
Eprint ID
17664
フルテキストURL
Thumnail 88_819.pdf 2.31 MB
タイトル(別表記)
Studies of intravenous galactose tolerance test on various liver diseases Part Ⅱ. A clinical significance of intravenous galactose tolerance test to various liver diseases:
著者
井上 武紀 岡山大学医学部第一内科教室
抄録
An intravenous galactose tolerance test with single injection of galactose of 175 mg/Kg body weight were performed in the patients with various liver diseases who admitted to The Okayama University Hospital, and half time of galactose disappearance (Gal T(1/2))was obtained. 1. The normal value of Gal T(1/2) was 10.5±1.9 min. and Gal T(1/2) values in the patients with acute hepatitis in icteric stage and in convalescent stage were 14.2±6.9 and 11.3±1.3 min. In the patients with chronic hepatitis and precirrhosis, Gal T(1/2) were 11.4±1.5 and 13.3±1.9 min., respectively. Gal T(1/2) values in cirrhotic patients were remarkably elevated up to 22.3±7.1 min. In patients with extrahepatic obstructive jaundice, Gal T(1/2) values were 12.4±2.4 min. and patients with intrabepatic cholestasis and fatty liver had normal Gal T(1/2) values. However, 2 out of 5 patients of extrahepatic obstructive jaundice showed elevated value of Gal T(1/2), in which cases secondary biliary cirrhosis was revealed at autopsy. 2. Gal T(1/2) values were closely correlated with KICG values and Gal T(1/2)/ICG T(1/2) value was appeared to be a marker for the differential diagnosis of parenchymal and obstructive jaundice. 3. Gal T(1/2) values were correlated well with KICG, BSP, serum albumin, serum gamma globulin, A/G ratio, ZST and blood NH(3) levels, but were not correlated with total serum bilirubin levels, ALP and S-GOT activities. 4. Histological examination showed that the elevation of Gal T(1/2) values were closely correlated with the development of fibrosis, disarrangement of hepatic lobules and hepatic cell necrosis. 5. The peritoneoscopic observation indicated that the Gal T(1/2) value appeaared to increase in parallel with completion of the nodular formation on the liver surface.
発行日
1976-10-30
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
88巻
9-10号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
819
終了ページ
830
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/88/9-10/88_9-10_819/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/
言語
Japanese
OAI-PMH Set
岡山大学
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Sort Key
10
Eprints Journal Name
joma