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ID 16438
Eprint ID
16438
フルテキストURL
Thumnail 95_1299.pdf 496 KB
タイトル(別表記)
Studies on Immunofunctional classification of non- Hodgkin's lymphoma (NHL) Part I. Correlation of the classification to chemotherapeutic response and survival
著者
石川 盛寛 岡山大学医学部第2内科学教室
抄録
To determine whether the analysis of lymphocyte surface markers provides clinically useful information, neoplastic cells from 51 adult patients with NHL were studied for surface markers and phagocytosis. The analysis revealed that NHL could be classified into four types according to the neoplastic cell type; T-cell, B-cell, Null-cell and true histiocyte types. On the basis of this immunofunctional classification, response to chemotherapy and survival of the patients were evaluated. The chemotherapeutic responsiveness rate (CR+PR rate) and complete remission (CR) rate of the T-cell type were shown to be the lowest in stage III and IV patients. Especially in stage IV, the CR rate of the T-cell type was statistically the lowest. Patients in both stages III and IV of the B-cell type survived the longest and those of the T-cell type, the shortest. In stage IV, the survival period of the T-cell type NHL patients was significantly shorter than those of the non-Burkitt B-cell type or Null-cell type. However, the difference between the survival of the B- and Null-cell types was not clear. These results indicate that the immunofunctional classification is some what useful for prediction of chemotherapeutic response and prognosis in NHL.
キーワード
Non-Hodgkin's lymphoma
Immunofunctional classification
Surface marker
Chemotherapy
発行日
1983-12-30
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
95巻
11-12号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
1299
終了ページ
1309
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/95/11-12/95_11-12_1299/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/index.html
言語
Japanese
OAI-PMH Set
岡山大学
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Sort Key
17
Eprints Journal Name
joma