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ID 46938
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Author
Kubo, Takanori
Matsuzaki, Rino
Endoh, Tamaki
Sisido, Masahiko
Abstract
A peptide nucleic acid (PNA)-cell-penetrating peptide (CPP) conjugate (carrier PNA) was used as 'bridgebuilder' to connect a CPP with an shRNA. The carrier PNA successfully formed a hybrid with an shRNA bearing complementary dangling bases and the shRNA was introduced into cells by the carrier PNA, and RNAi was induced by the shRNA.
Keywords
Peptide nucleic acid
Cell-penetrating peptide
RNA interference
Published Date
2009-07-01
Publication Title
Bioorganic & Medicinal Chemistry Letters
Volume
volume19
Issue
issue13
Publisher
Elsevier Ltd.
Start Page
3410
End Page
3413
ISSN
0960-894X
NCID
AA1079577X
Content Type
Journal Article
language
英語
Copyright Holders
Crown Copyright © 2009 Published by Elsevier Ltd. All rights reserved.
File Version
author
Refereed
True
DOI
PubMed ID
Web of Sience KeyUT