| JaLCDOI | 10.18926/AMO/60799 |
|---|---|
| FullText URL | 74_5_401.pdf |
| Author | Tsukioki, Takahiro| Shien, Tadahiko| Ohtani, Yusuke| Fujihara, Miwa| Suzuki, Yoko| Kajihara, Yukiko| Hatono, Minami| Kawada, Kengo| Kochi, Mariko| Iwamoto, Takayuki| Ikeda, Hirokuni| Taira, Naruto| Doihara, Hiroyoshi| |
| Abstract | Differentiated thyroid carcinoma (DTC) in juvenile patients is often an extensive and aggressive disease with a high frequency of recurrence. However, the prognosis is excellent, with a low mortality rate even when advanced disease is present, although prognostic factors and treatment strategy remain uncertain. Between April 2004 and March 2017, 33 juvenile patients (< 30 years old) were diagnosed with DTC and treated at our institution. We retrospectively investigated prognosis and factors including sex, reason for discovery, treatment, pathological factors and treatment progress to clarify the risk factors. All patients underwent curative surgical treatment. Pathologically, lymph node metastasis was identified in 25 patients (75%). Thirteen patients (39%) had bilateral cervical metastasis. In addition, 9 (27%) had more than 10 metastatic lymph nodes. The 2 patients with more than 20 metastatic lymph nodes were treated with radioactive iodine (RAI). Five patients (15%) had local recurrences and received surgery. There have been no further recurrences or deaths. However, no factors were determined to significantly predict the recurrence of juvenile DTC. Local recurrent disease was treated with surgery and/or RAI until remission, and survival was excellent in juvenile DTC. |
| Keywords | differentiated thyroid carcinoma juvenile children |
| Amo Type | Original Article |
| Published Date | 2020-10 |
| Publication Title | Acta Medica Okayama |
| Volume | volume74 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 401 |
| End Page | 406 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | 英語 |
| Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 33106695 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Tsukioki, Takahiro| Shien, Tadahiko| Doihara, Hiroyoshi| |
| Keywords | Breast cancer metastatic stage IV local therapy locoregional therapy surgery survival |
| Published Date | 2020-08 |
| Publication Title | Translational Cancer Research |
| Volume | volume9 |
| Issue | issue8 |
| Publisher | AME Publishing Co. |
| Start Page | 5102 |
| End Page | 5107 |
| ISSN | 2218-676X |
| Content Type | Journal Article |
| language | 英語 |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © Translational Cancer Research. All rights reserved. |
| File Version | publisher |
| DOI | 10.21037/tcr.2020.01.60 |
| Web of Science KeyUT | 000562138400067 |
| Related Url | isVersionOf https://doi.org/10.21037/tcr.2020.01.60 |
| Author | Ochi, Kosuke| Suzawa, Ken| Tomida, Shuta| Shien, Kazuhiko| Takano, Jui| Miyauchi, Shunsaku| Takeda, Tatsuaki| Miura, Akihiro| Araki, Kota| Nakata, Kentaro| Yamamoto, Hiromasa| Okazaki, Mikio| Sugimoto, Seiichiro| Shien, Tadahiko| Yamane, Masaomi| Azuma, Kazuo| Okamoto, Yoshiharu| Toyooka, Shinichi| |
|---|---|
| Keywords | Monensin Epithelial-mesenchymal transition Non-small cell lung cancer Drug repositioning Drug resistance |
| Note | This fulltext is available in Jul. 2021.| |
| Published Date | 2020-08-27 |
| Publication Title | Biochemical and Biophysical Research Communications |
| Volume | volume529 |
| Issue | issue3 |
| Publisher | Academic Press |
| Start Page | 760 |
| End Page | 765 |
| ISSN | 0006-291X |
| NCID | AA00564395 |
| Content Type | Journal Article |
| language | 英語 |
| OAI-PMH Set | 岡山大学 |
| File Version | Author |
| PubMed ID | 32736704 |
| DOI | 10.1016/j.bbrc.2020.06.077 |
| Web of Science KeyUT | 000555780500037 |
| Related Url | iaVersionOf https://doi.org/10.1016/j.bbrc.2020.06.077 |
| FullText URL | CCP_fulltext.pdf |
|---|---|
| Author | Tsukioki, Takahiro| Shien, Tadahiko| Tanaka, Takehiro| Suzuki, Yoko| Kajihara, Yukiko| Hatono, Minami| Kawada, Kengo| Kochi, Mariko| Iwamoto, Takayuki| Ikeda, Hirokuni| Taira, Naruto| Doihara, Hiroyoshi| Toyooka, Shinichi| |
| Keywords | Breast cancer Metformin Preoperative Tils CD8 PD-L1 |
| Published Date | 2020-06-12 |
| Publication Title | Cancer Chemotherapy and Pharmacology |
| Volume | volume86 volume86 |
| Issue | issue1 issue1 |
| Publisher | Springer |
| Start Page | 55 55 |
| End Page | 63 63 |
| ISSN | 0344-5704 |
| NCID | AA00598397 |
| Content Type | Journal Article |
| language | 英語 |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | ©Author(s) |
| File Version | Publisher |
| PubMed ID | 32533334 |
| DOI | 10.1007/s00280-020-04092-2 |
| Web of Science KeyUT | 000539841500002 |
| Related Url | isVersionOf https://doi.org/10.1007/s00280-020-04092-2 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Shien, Tadahiko| |
| Published Date | 2019-03 |
| Publication Title | Translational Cancer Research |
| Volume | volume8 |
| Issue | issueSuppl. 2 |
| Publisher | AME Publishing |
| Start Page | S118 |
| End Page | S119 |
| ISSN | 2218-676X |
| Content Type | Journal Article |
| language | 英語 |
| OAI-PMH Set | 岡山大学 |
| File Version | publisher |
| DOI | 10.21037/tcr.2018.11.19 |
| Related Url | isVersionOf https://doi.org/10.21037/tcr.2018.11.19 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Shien, Tadahiko| Iwata, Hiroji| |
| Keywords | breast cancer adjuvant neoadjuvant |
| Note | This is a pre-copyedited, author-produced version of an article accepted for publication in Japanese Journal of Clinical Oncology following peer review. The version of record TTadahiko Shien, Hiroji Iwata, Adjuvant and neoadjuvant therapy for breast cancer, Japanese Journal of Clinical Oncology, Volume 50, Issue 3, March 2020, Pages 225–229 is available online at: https://doi.org/10.1093/jjco/hyz213.| |
| Published Date | 2020-01-28 |
| Publication Title | Japanese Journal of Clinical Oncology |
| Volume | volume50 |
| Issue | issue3 |
| Publisher | Oxford University Press |
| Start Page | 225 |
| End Page | 229 |
| ISSN | 0368-2811 |
| NCID | AA00690866 |
| Content Type | Journal Article |
| language | 英語 |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | Copyright © 2020 Oxford University Press |
| File Version | author |
| PubMed ID | 32147701 |
| DOI | 10.1093/jjco/hyz213 |
| Web of Science KeyUT | 000536439500001 |
| Related Url | isVersionOf https://doi.org/10.1093/jjco/hyz213 |
| Author | Iwamoto, Takayuki| Fujisawa, Tomomi| Shien, Tadahiko| Araki, Kazuhiro| Sakamaki, Kentaro| Sangai, Takafumi| Kikawa, Yuichiro| Takao, Shintaro| Nishimura, Reiki| Takahashi, Masato| Aihara, Tomohiko| Mukai, Hirofumi| aira, Naruto| |
|---|---|
| Keywords | Metastatic breast cancer Endocrine therapies Estrogen receptor-positive HER2-negative Resistance |
| Note | This fulltext is available in May 2021.| |
| Published Date | 2020-05-11 |
| Publication Title | Breast Cancer |
| Publisher | Springer |
| ISSN | 13406868 |
| NCID | AA1103354X |
| Content Type | Journal Article |
| language | 英語 |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| PubMed ID | 32394413 |
| DOI | 10.1007/s12282-020-01095-y |
| Web of Science KeyUT | 000531780600002 |
| Related Url | isVersionOf https://doi.org/10.1007/s12282-020-01095-y |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Takeda, Tatsuaki| Yamamoto, Hiromasa| Suzawa, Ken| Tomida, Shuta| Miyauchi, Shunsaku| Araki, Kota| Nakata, Kentaro| Miura, Akihiro| Namba, Kei| Shien, Kazuhiko| Soh, Junichi| Shien, Tadahiko| Kitamura, Yoshihisa| Sendo, Toshiaki| Toyooka, Shinichi| |
| Keywords | breast cancer drug resistance lung cancer neratinib YES1 |
| Published Date | 2019-12-19 |
| Publication Title | Cancer Science |
| Volume | volume111 |
| Issue | issue3 |
| Publisher | Wiley |
| Start Page | 849 |
| End Page | 856 |
| ISSN | 1347-9032 |
| Content Type | Journal Article |
| language | 英語 |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2019 The Authors. |
| File Version | publisher |
| PubMed ID | 31856375 |
| DOI | 10.1111/cas.14289 |
| Web of Science KeyUT | 000507433400001 |
| Related Url | isVersionOf https://doi.org/10.1111/cas.14289 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Suzuki, Yoko| Taniguchi, Kohei| Hatono, Minami| Kajiwara, Yukiko| Abe, Yuko| Kawada, Kengo| Tsukioki, Takahiro| Kochi, Mariko| Nishiyama, Keiko| Iwamoto, Takayuki |
