Otsuka, Fumio - OU Author List - OKAYAMA UNIVERSITY SCIENTIFIC ACHIEVEMENT REPOSITORY

Association of initial interface formation time with CD34+ collection efficiency in continuous mononuclear cell collection: A retrospective study

FullText URL	fulltext.pdf
Author	Murakami, Hiroyuki\| Fujii, Keiko\| Kitamura, Wataru\| Ikeuchi, Kazuhiro\| Shimono, Joji\| Otsuka, Fumio\| Maeda, Yoshinobu\| Fujii, Nobuharu\|
Keywords	CD34+CE2 Continuous mononuclear cell collection Spectra Optia Interface formation time Leukapheresis
Published Date	2026-10
Publication Title	Transfusion and Apheresis Science
Volume	volume65
Issue	issue5
Publisher	Elsevier BV
Start Page	104504
ISSN	1473-0502
NCID	AA11555942
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2026 The Authors.
File Version	publisher
PubMed ID	42531747
DOI	10.1016/j.transci.2026.104504
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Autopsy Case of a Disseminated Cytomegalovirus Infection with a Cutaneous Ulcer Mimicking Rheumatoid Vasculitis

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Author	Oguni, Kohei\| Hagiya, Hideharu\| Yamamoto, Yukichika\| Ishida, Tomoharu\| Ohki, Tomoka\| Otsuka, Fumio\|
Keywords	autopsy cytomegalovirus cutaneous cytomegalovirus virus-associated hemophagocytic syndrome rheumatoid vasculitis
Published Date	2026-04-15
Publication Title	Internal Medicine
Volume	volume65
Issue	issue8
Publisher	Japanese Society of Internal Medicine
Start Page	1172
End Page	1177
ISSN	0918-2918
NCID	AA10827774
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2026 by The Japanese Society of Internal Medicine
File Version	publisher
PubMed ID	40903227
DOI	10.2169/internalmedicine.5990-25
Web of Science KeyUT	001564005800001
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Nasal Mucosal Manifestation of Behçet's Disease

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Author	Akiyama, Hiroshi\| Otsuka, Yuki\| Masuda, Yohei\| Soejima, Yoshiaki\| Nakamoto, Kenta\| Katayama, Yu\| Sato, Aki\| Hagiya, Hideharu\| Otsuka, Fumio\|
Keywords	Behçet's disease nasal mucosal manifestation apremilast colchicine prednisolone
Published Date	2026-04-01
Publication Title	Internal Medicine
Volume	volume65
Issue	issue7
Publisher	Japanese Society of Internal Medicine
Start Page	1069
End Page	1073
ISSN	0918-2918
NCID	AA10827774
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2026 by The Japanese Society of Internal Medicine
File Version	publisher
PubMed ID	40866267
DOI	10.2169/internalmedicine.6014-25
CRID	1390870696577092992
Web of Science KeyUT	001559836000001
Related Url	isVersionOf https://doi.org/10.2169/internalmedicine.6014-25

A Case of Heavy Paragonimiasis Involving a Multi-Organ Presentation with Hypereosinophilia and Hepatic Migration

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Author	Akazawa, Hidemasa\| Hagiya, Hideharu\| Fukushima, Shinnosuke\| Nakamoto, Kenta\| Oguni, Kohei\| Manabe, Yohei\| Kokubo-Tanaka, Mio\| Maruyama, Haruhiko\| Otsuka, Fumio\|
Published Date	2026-03-04
Publication Title	The American Journal of Tropical Medicine and Hygiene
Volume	volume114
Issue	issue3
Publisher	American Society of Tropical Medicine and Hygiene
Start Page	486
End Page	489
ISSN	0002-9637
NCID	AA00521439
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2026 The author(s)
File Version	publisher
PubMed ID	41666460
DOI	10.4269/ajtmh.25-0392
Web of Science KeyUT	001715134600019
Related Url	isVersionOf https://doi.org/10.4269/ajtmh.25-0392

Mycobacterium intracellulare Infection in a Japanese Patient with Signal Transducer and Activator of Transcription-3 Gain-of-function Syndrome

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Author	Hagiya, Hideharu\| Soejima, Yoshiaki\| Tokumasu, Kazuki\| Hirai, Yoji\| Otsuka, Yuki\| Kawaguchi, Marina\| Fukushima, Shinnosuke\| Nakamoto, Kenta\| Oguni, Kohei\| Shiode, Yusuke\| Uda, Kazuhiro\| Yashiro, Masato\| Hasegawa, Kousei\| Iio, Koji\| Otsuka, Fumio\|
Keywords	inborn errors of immunity Mycobacterium avium complex nontuberculous mycobacteria primary immunodeficiency syndrome signal transducer and activator of transcription-3
Published Date	2026-05-15
Publication Title	Internal Medicine
Volume	volume65
Issue	issue10
Publisher	Japanese Society of Internal Medicine
Start Page	1421
End Page	1430
ISSN	0918-2918
NCID	AA10827774
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2026 by The Japanese Society of Internal Medicine
File Version	publisher
PubMed ID	41034003
DOI	10.2169/internalmedicine.6174-25
Web of Science KeyUT	001586962100001
Related Url	isVersionOf https://doi.org/10.2169/internalmedicine.6174-25

Behavior of serum thyroglobulin in relation to thyroid function under low-thyrotropin conditions in general practice

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Author	Sazumi, Yosuke\| Soejima, Yoshiaki\| Otsuka, Yuki\| Nakano, Yasuhiro\| Yamamoto, Koichiro\| Suyama, Atsuhito\| Takase, Ryosuke\| Oguni, Kohei\| Yasuda, Miho\| Furukawa, Masanori\| Otsuka, Fumio\|
Keywords	FT3/FT4 ratio hyperthyroidism iodothyronine deiodinase thyroglobulin TSH- receptor antibody
Published Date	2026-05-15
Publication Title	Frontiers in Endocrinology
Volume	volume17
Publisher	Frontiers Media SA
Start Page	1756863
End Page	1756863
ISSN	1664-2392
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2026 Sazumi, Soejima, Otsuka, Nakano, Yamamoto, Suyama, Takase, Oguni, Yasuda, Furukawa and Otsuka.
File Version	publisher
PubMed ID	42222078
DOI	10.3389/fendo.2026.1756863
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CPPD-Induced Iliopsoas Bursitis Mimicking Pyomyositis

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Author	Okunobu, Hiroki\| Fukushima, Shinnosuke\| Hagiya, Hideharu\| Otsuka, Fumio\|
Keywords	16S rRNA abscess calcium pyrophosphate deposition disease culture-negative direct sequencing analysis
Published Date	2026-05-25
Publication Title	Clinical Case Reports
Volume	volume14
Issue	issue6
Publisher	Wiley
Start Page	e72814
ISSN	2050-0904
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2026 The Author(s).
File Version	publisher
PubMed ID	42256962
DOI	10.1002/ccr3.72814
Web of Science KeyUT	001775651200001
Related Url	isVersionOf https://doi.org/10.1002/ccr3.72814

Exploratory Analysis of Serum IGF-I Levels and Symptom Trajectories in Long COVID During the Omicron Period

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Author	Suyama, Atsuhito\| Otsuka, Yuki\| Nakano, Yasuhiro\| Tokumasu, Kazuki\| Sakurada, Yasue\| Matsuda, Yui\| Honda, Hiroyuki\| Soejima, Yoshiaki\| Hasegawa, Toru\| Takase, Ryosuke\| Omura, Daisuke\| Oguni, Kohei\| Ueda, Keigo\| Otsuka, Fumio\|
Keywords	COVID-19 fatigue IGF-I long COVID recovery
Published Date	2026-05-11
Publication Title	Journal of Clinical Medicine
Volume	volume15
Issue	issue10
Publisher	MDPI AG
Start Page	3702
ISSN	2077-0383
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2026 by the authors.
File Version	publisher
PubMed ID	42194664
DOI	10.3390/jcm15103702
Web of Science KeyUT	001776414600001
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Possible Involvement of Hypothalamic Dysfunction in Long COVID Patients Characterized by Delayed Response to Gonadotropin-Releasing Hormone

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Author	Otsuka, Yuki\| Soejima, Yoshiaki\| Nakano, Yasuhiro\| Suyama, Atsuhito\| Takase, Ryosuke\| Oguni, Kohei\| Masuda, Yohei\| Omura, Daisuke\| Sakurada, Yasue\| Matsuda, Yui\| Hasegawa, Toru\| Honda, Hiroyuki\| Tokumasu, Kazuki\| Ueda, Keigo\| Otsuka, Fumio\|
Keywords	COVID-19 gonadotropin gonadotropin-releasing hormone (GnRH) hypothalamus long COVID
Published Date	2026-01-14
Publication Title	International Journal of Molecular Sciences
Volume	volume27
Issue	issue2
Publisher	MDPI AG
Start Page	832
ISSN	1422-0067
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2026 by the authors.
File Version	publisher
PubMed ID	001670615000001
DOI	10.3390/ijms27020832
Web of Science KeyUT	001670615000001
Related Url	isVersionOf https://doi.org/10.3390/ijms27020832

Clinical Utility of SARS-CoV-2 Antibody Titers in the Management of Patients With Long COVID Infected With the Omicron Variant

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Author	Kawaguchi, Marina\| Sakurada, Yasue\| Tokumasu, Kazuki\| Otsuka, Yuki\| Nakano, Yasuhiro\| Matsuda, Yui\| Honda, Hiroyuki\| Omura, Daisuke\| Matsuki, Nobuyoshi\| Furukawa, Masanori\| Higashikage, Akihito\| Otsuka, Fumio\|
Keywords	brain fog COVID-19 long COVID Omicron variants SARS-CoV-2 antibodies
Published Date	2026-04-22
Publication Title	British Journal of Biomedical Science
Volume	volume83
Publisher	Frontiers Media SA
Start Page	16255
ISSN	2474-0896
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2026 Kawaguchi, Sakurada, Tokumasu, Otsuka, Nakano, Matsuda, Honda, Omura, Matsuki, Furukawa, Higashikage and Otsuka.
File Version	publisher
DOI	10.3389/bjbs.2026.16255
Web of Science KeyUT	001757232800001
Related Url	isVersionOf https://doi.org/10.3389/bjbs.2026.16255

Changes in Prescribing Patterns of Antiviral Drugs before and after Public Coverage Termination among Hospitalized COVID-19 Patients in Regional Hospitals in Japan: A Retrospective, Multicenter Study

JaLCDOI	10.18926/AMO/70073
FullText URL	80_1_055.pdf
Author	Akazawa, Hidemasa\| Hagiya, Hideharu\| Fukushima, Shinnosuke\| Yamamoto, Shohei\| Nakano, Yasuhiro\| Otsuka, Fumio\|
Abstract	In Japan, antiviral agents for COVID-19 were freely available until September 2023 as part of national policy. This study evaluated changes in these agents’ prescribing patterns and the patient outcomes following the policy shift. We conducted a multicenter retrospective study at four hospitals in Japan’s Okayama and Kagawa prefectures from January 2022 to March 2024. The study period was divided into the public-expenditure phase (January 2022 to September 2023) and the post-expenditure phase (October 2023 to March 2024). We extracted the hospitalized patients’ clinical data from the electronic database. The study’s primary outcome was the antiviral prescription rate; the secondary outcome was in-hospital mortality. Among the 302 hospitalized patients (median age 85 years), 52.0% were classified as having a mild condition. Of the patients with mild conditions, 37.7% were diagnosed in outpatient settings prior to hospitalization. During the public-expenditure phase, 47.4% of the patients received antivirals as outpatients, mainly molnupiravir (80.9%). In the post-expenditure period, 80.0% of the patients were prescribed antivirals, mostly molnupiravir (91.7%). The antiviral prescription rate was significantly higher after the policy change. The overall in-hospital mortality was 15.8%, with no significant difference between the two periods (17.0% vs. 10.5%). Despite the termination of government funding, antiviral prescriptions remained frequent at community hospitals located in highly aging regions of western Japan such as Okayama and Kagawa prefectures. Mortality remains high among the elderly, highlighting the need for continued antiviral therapy and booster vaccinations.
Keywords	coronavirus disease 2019 public expenditure prescribing pattern prognosis Japan
Amo Type	Original Article
Publication Title	Acta Medica Okayama
Published Date	2026-02
Volume	volume80
Issue	issue1
Publisher	Okayama University Medical School
Start Page	55
End Page	62
ISSN	0386-300X
NCID	AA00508441
Content Type	Journal Article
language	English
Copyright Holders	Copyright Ⓒ 2026 by Okayama University Medical School
File Version	publisher
Refereed	True
PubMed ID	41748150
Web of Science KeyUT	001712994500007

Pediatric autologous peripheral blood stem cell collection without heparin using a highly concentrated sodium citrate anticoagulant: A retrospective comparison with standard ACD-A

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Author	Fujii, Keiko\| Kitamura, Wataru\| Washio, Kana\| Ikeuchi, Kazuhiro\| Shimono, Joji\| Murakami, Hiroyuki\| Otsuka, Fumio\| Maeda, Yoshinobu\| Fujii, Nobuharu\|
Keywords	acid citrate dextrose solution autologous continuous mononuclear cell collection highly concentrated sodium pediatric peripheral blood stem cells
Published Date	2026-02-02
Publication Title	Transfusion
Publisher	Wiley
ISSN	0041-1132
NCID	AA00868753
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2026 The Author(s).
File Version	publisher
PubMed ID	41630350
DOI	10.1111/trf.70102
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Whole-genome sequencing and in vitro characterization of a disseminated ST398 Staphylococcus aureus infection: A case report

Author	Sazumi, Yosuke\| Fukushima, Shinnosuke\| Hagiya, Hideharu\| Kato, Atsushi\| Suyama, Atsuhito\| Oguni, Kohei\| Gotoh, Kazuyoshi\| Kutsuno, Shoko\| Hisatsune, Junzo\| Sugai, Motoyuki\| Tsuji, Shuma\| Iio, Koji\| Otsuka, Fumio\|
Keywords	Staphylococcus aureus Sequence type 398 Disseminated infection Immune evasion cluster gene
Note	© 2025 Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases, and Japanese Society for Infection Prevention and Control. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/\| This fulltext file will be available in Oct. 2026.\|
Published Date	2025-12
Publication Title	Journal of Infection and Chemotherapy
Volume	volume31
Issue	issue12
Publisher	Elsevier BV
Start Page	102845
ISSN	1341-321X
NCID	AA11057978
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2025 Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases, and Japanese Society for Infection Prevention and Control.
File Version	author
PubMed ID	41161474
DOI	10.1016/j.jiac.2025.102845
Web of Science KeyUT	001611880300001
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Cerebellar abscess caused by Cladophialophora bantiana involving an elderly Japanese woman

FullText URL	fulltext20260111-01.pdf
Author	Nakamoto, Kenta\| Hagiya, Hideharu\| Fukushima, Shinnosuke\| Oguni, Kohei\| Yokoyama, Yukika\| Iio, Koji\| Hirano, Shuichiro\| Yaguchi, Takashi\| Ban, Sayaka\| Watanabe, Akira\| Okunobu, Hiroki\| Suyama, Atsuhito\| Kawaguchi, Marina\| Sazumi, Yousuke\| Otsuka, Fumio\|
Keywords	Brain abscess Cladophialophora bantiana Black fungus Phaeohyphomycosis Posaconazole
Note	© 2025 SFMM. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/\| This fulltext file will be available in Mar. 2026.\|
Published Date	2025-06
Publication Title	Journal of Medical Mycology
Volume	volume35
Issue	issue2
Publisher	Elsevier BV
Start Page	101548
ISSN	1156-5233
NCID	AA11001383
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2025 SFMM.
File Version	author
PubMed ID	40168940
DOI	10.1016/j.mycmed.2025.101548
Web of Science KeyUT	001460918900001
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Focal Nodular Hyperplasia of the Liver Mimicking Gastric Submucosal Tumor

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Author	Masuda, Yohei\| Otsuka, Yuki\| Soejima, Yoshiaki\| Otsuka, Fumio\|
Keywords	extragastric compression focal liver lesions focal nodular hyperplasia gastric submucosal tumor spoke-wheel pattern
Published Date	2025-12
Publication Title	Clinical Case Reports
Volume	volume13
Issue	issue12
Publisher	Wiley
Start Page	e71666
ISSN	2050-0904
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2025 The Author(s).
File Version	publisher
PubMed ID	41368062
DOI	10.1002/ccr3.71666
Web of Science KeyUT	001633808000001
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Molecular epidemiological investigation of the carbapenemase-producing Enterobacterales isolates in Okayama prefecture, Japan

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Author	Tsuji, Shuma\| Fukushima, Shinnosuke\| Gotoh, Kazuyoshi\| Iio, Koji\| Sato, Mayu\| Inoue, Yasurou\| Sakita, Sayaka\| Fudeyasu, Tomoko\| Otsuka, Fumio\| Hagiya, Hideharu\|
Keywords	Antimicrobial resistance Carbapenemase-producing Enterobacterales New Delhi metallo-β-lactamase Klebsiella pneumoniae carbapenemase Genomic surveillance
Published Date	2026-03
Publication Title	Diagnostic Microbiology and Infectious Disease
Volume	volume114
Issue	issue3
Publisher	Elsevier BV
Start Page	117209
ISSN	0732-8893
NCID	AA10623322
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2025 The Author(s).
File Version	publisher
PubMed ID	41343892
DOI	10.1016/j.diagmicrobio.2025.117209
Web of Science KeyUT	001635147000001
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Interaction Between Thyroid Hormones and Bone Morphogenetic Proteins in the Regulation of Steroidogenesis by Granulosa Cells

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Author	Motohashi, Kanon\| Soejima, Yoshiaki\| Yamamoto, Koichiro\| Iwata, Nahoko\| Suyama, Atsuhito\| Nakano, Yasuhiro\| Otsuka, Fumio\|
Keywords	bone morphogenetic protein (BMP) thyroid hormone steroidogenesis ovary
Published Date	2025-09-18
Publication Title	International Journal of Molecular Sciences
Volume	volume26
Issue	issue18
Publisher	MDPI AG
Start Page	9127
ISSN	1422-0067
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2025 by the authors.
File Version	publisher
PubMed ID	41009688
DOI	10.3390/ijms26189127
Web of Science KeyUT	001580156800001
Related Url	isVersionOf https://doi.org/10.3390/ijms26189127

Clinical Evaluation of Oxidative Stress Markers in Patients with Long COVID During the Omicron Phase in Japan

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Author	Mese, Osamu\| Otsuka, Yuki\| Sakurada, Yasue\| Tokumasu, Kazuki\| Soejima, Yoshiaki\| Morita, Satoru\| Nakano, Yasuhiro\| Honda, Hiroyuki\| Eguchi, Akiko\| Fukuda, Sanae\| Nojima, Junzo\| Otsuka, Fumio\|
Keywords	biological antioxidant potential (BAP) Coronavirus disease 2019 (COVID-19) diacron-reactive oxygen metabolites (d-ROM) Long COVID oxidative stress index (OSI)
Published Date	2025-08-30
Publication Title	Antioxidants
Volume	volume14
Issue	issue9
Publisher	MDPI AG
Start Page	1068
ISSN	2076-3921
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2025 by the authors.
File Version	publisher
PubMed ID	41008975
DOI	10.3390/antiox14091068
Web of Science KeyUT	001579416500001
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Factors affecting the development of hypokalemia during apheresis in healthy donors

FullText URL	fulltext.pdf
Author	Kitamura, Wataru\| Fujii, Keiko\| Kobayashi, Hiroki\| Abe, Masaya\| Fukumi, Takuya\| Ikeuchi, Kazuhiro\| Otsuka, Fumio\| Maeda, Yoshinobu\| Fujii, Nobuharu\|
Keywords	Allogeneic Peripheral blood stem cells Hypokalemia Acid citrate dextrose solution A Healthy donors
Published Date	2025-08
Publication Title	Transfusion and Apheresis Science
Volume	volume64
Issue	issue4
Publisher	Elsevier BV
Start Page	104195
ISSN	1473-0502
NCID	AA11555942
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2025 The Authors.
File Version	publisher
PubMed ID	40561934
DOI	10.1016/j.transci.2025.104195
Web of Science KeyUT	10.1016/j.transci.2025.104195
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Symptomatic Trends and Time to Recovery for Long COVID Patients Infected During the Omicron Phase

FullText URL	fulltext.pdf
Author	Akiyama, Hiroshi\| Sakurada, Yasue\| Honda, Hiroyuki\| Matsuda, Yui\| Otsuka, Yuki\| Tokumasu, Kazuki\| Nakano, Yasuhiro\| Takase, Ryosuke\| Omura, Daisuke\| Ueda, Keigo\| Otsuka, Fumio\|
Keywords	fatigue headache insomnia long COVID Omicron variants recovery
Published Date	2025-07-11
Publication Title	Journal of Clinical Medicine
Volume	volume14
Issue	issue14
Publisher	MDPI AG
Start Page	4918
ISSN	2077-0383
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2025 by the authors.
File Version	publisher
PubMed ID	40725611
DOI	10.3390/jcm14144918
Web of Science KeyUT	001535803000001
Related Url	isVersionOf https://doi.org/10.3390/jcm14144918