| Author | Nasu, Yasutomo| |
|---|---|
| Published Date | 2008-08-01 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume120 |
| Issue | issue2 |
| Content Type | Journal Article |
| Author | Kobuke, Makoto| Nasu, Yasutomo| Kumon, Hiromi| |
|---|---|
| Published Date | 2008-08-01 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume120 |
| Issue | issue2 |
| Content Type | Journal Article |
| Author | 那須 保友| 公文 裕巳| |
|---|---|
| Published Date | 2002-09-30 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume114 |
| Issue | issue2 |
| Content Type | Journal Article |
| JaLCDOI | 10.18926/AMO/31599 |
|---|---|
| FullText URL | fulltext.pdf |
| Author | Kuroda, Masahiro| Tsushima, Tomoyasu| Nasu, Yasutomo| Asaumi, Junichi| Nishikawa, Koji| Gao, Xian Shu| Joja, Ikuo| Takeda, Yoshihiro| Togami, Izumi| Makihata, Eiichi| Kawasaki, Shoji| Ohmori, Hiroyuki| Hiraki, Yoshio| |
| Abstract | <p>We performed a long-term follow-up of 4 patients with penile cancer who underwent hyperthermotherapy from August 1985 until August 1992. Hyperthermia was applied using a frequency of 350 MHz with a waveguide applicator twice a week for 60 min each for an average of 9.5 times (varying from 6 to 13 times). The total heating time that the temperature of urethra could be kept above 42 degrees C, was 166 min on the average (ranging from 0 to 463 min). Two patients classified as stage I according to the Jackson classification and 1 patient classified as stage IV underwent combined radiotherapy and received an average radiation dose of 53 Gy (range, 40-70 Gy). Among these patients 2 underwent combined chemotherapy with bleomycin or peplomycin. Malignant cells disappeared posttherapeutically and in August 1992, after an average of 5 years and 9 months (varying from 4 years 6 months to 6 years 10 months), the patients were free of recurrences. The one patient on stage IV had extensive invasion of the abdominal wall, but still recovered completely. One patient on stage III underwent combined chemotherapy and hyperthermotherapy, but heating had obviously been insufficient. There was a residue of malignant cells after the treatment and we performed a penectomy. Regarding functional preservation of the penis a multidisciplinary therapy incorporating hyperthermotherapy can be expected to increase the curativity. This indicates that it could induce in an advanced case, where an operation would be difficult, complete remission.</p> |
| Keywords | penile cancer hyperthermia radiotherapy chemotherapy |
| Amo Type | Article |
| Published Date | 1993-06 |
| Publication Title | Acta Medica Okayama |
| Volume | volume47 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 169 |
| End Page | 174 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | 英語 |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 8379345 |
| Web of Science KeyUT | A1993LL12400005 |
| JaLCDOI | 10.18926/AMO/31722 |
|---|---|
| FullText URL | fulltext.pdf |
| Author | Nagai, Atsushi| Nasu, Yasutomo| Shirasaki, Yoshinori| Iguchi, Hiroki| Arata, Ryouji| Tsugawa, Masaya| Tsushima, Tomoyasu| Kumon, Hiromi| |
| Abstract | <p>We performed laparoscopic prostatectomy in seven cases with organ-confined prostate cancer. In 6 cases, the surgery was completed successfully and the mean operative time was 424 min. Volume of blood loss was 200 to 3,200 ml and catheterization lasted 6 to 37 days. No major complications were observed in 6 of the cases. In one case, open surgical conversion was necessary mainly due to a bladder injury. Although these were the first cases of laparoscopic prostatectomy in our institution, the technical difficulty and complexity of the surgery were moderate. We believe that laparoscopic radical prostatectomy will become a standard option for the treatment of organ-confined prostate cancer.</p> |
| Keywords | prosatatic cancer laparoscopy prostatectomy |
| Amo Type | Article |
| Published Date | 2002-02 |
| Publication Title | Acta Medica Okayama |
| Volume | volume56 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 51 |
| End Page | 52 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | 英語 |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 11873945 |
| Web of Science KeyUT | 000174031300009 |
| JaLCDOI | 10.18926/AMO/31847 |
|---|---|
| FullText URL | fulltext.pdf |
| Author | Kobuke, Makoto| Saika, Takashi| Nakanishi, Yoshiko| Ebara, Shin| Manabe, Daisuke| Uesugi, Tatsuya| Nose, Hiroyuki| Arata, Ryoji| Tsushima, Tomoyasu| Nasu, Yasutomo| Kumon, Hiromi| |
| Abstract | <p>To determine health-related quality of life (HRQOL) after radical retropubic prostatectomy (RRP) or permanent prostate brachytherapy (BT), third party-conducted QOL surveys were prospectively compared. Between 2004 and 2005, 37 patients underwent RRP and 36 were treated with BT. A QOL survey consisting of the Medical Outcomes Study 36-Item Short Form (SF-36), the University of California, Los Angeles, Prostate Cancer Index (UCLA-PCI) and the International Prostate Symptoms Score (IPSS) was completed prospectively by a research coordinator at baseline, and at 1, 3, 6 and 12 months after treatment. The RRP patients scored well in general QOL except at 1 month after surgery, with their mental health better than at baseline by 6 months after surgery. Disease-specific QOL in RRP patients received a low score at 1 month for both urinary and sexual function, though urinary function rapidly recovered to baseline levels. BT patient QOL was not affected by the therapy except in the IPSS score. However, general and mental health scores in BT patients were inferior to those in RRP patients. This prospective study revealed differences in QOL after RRP and BT. These results will be helpful in making treatment decisions.</p> |
| Keywords | prostate cancer radical prostatectomy QOL brachytherapy |
| Amo Type | Original Article |
| Published Date | 2009-06 |
| Publication Title | Acta Medica Okayama |
| Volume | volume63 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 129 |
| End Page | 135 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | 英語 |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 19571899 |
| Web of Science KeyUT | 000267388200002 |
| JaLCDOI | 10.18926/AMO/32084 |
|---|---|
| FullText URL | fulltext.pdf |
| Author | Abarzua, Fernando| Monden, Koichi| Nagai, Atsushi| Nasu, Yasutomo| Kumon, Hiromi| |
| Abstract | <p>Ureteroscopy has evolved in many aspects, particularly in the flexibility and size of ureteroscopes. We have developed a new detachable access sheath to make ureteroscopic procedures more straight-forward and to reduce possible damage to delicate instruments used in the procedure.</p> |
| Keywords | ureteroscopy detachable accesss heath |
| Amo Type | Article |
| Published Date | 2004-08 |
| Publication Title | Acta Medica Okayama |
| Volume | volume58 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 215 |
| End Page | 216 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | 英語 |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 15551759 |
| Web of Science KeyUT | 000223559700006 |
| JaLCDOI | 10.18926/AMO/32868 |
|---|---|
| FullText URL | fulltext.pdf |
| Author | Arata, Ryoji| Saika, Takashi| Tsushima, Tomoyasu| Abarzua, Fernando| Nasu, Yasutomo| Kumon, Hiromi| |
| Abstract | To compare the quality of life (QOL) in patients with ileal neobladder and sigmoidal neobladder, a retrospective survey was conducted using a formulated questionnaire. Between January and March 1999, a QOL survey was conducted using self-administered questionnaires (EORTC QLQ-C30, IPSS, supplemented with detailed questionnaires about continence, sexual function, and patient’s satisfaction with the selected urinary diversion method) for 78 patients with orthotopic urinary reservoir (OUR) who were followed-up for more than 3 months after cystectomy. Among 78 patients, 63 had OUR using an ileal segment (male/female＝59/4, median age: 70.8 years old, median follow-up: 1.7 years). Fifteen patients had OUR using a sigmoidal segment (male/female＝13/2, median age: 71.9, median follow-up: 3.9). The QLQ-C30 functional evaluation and the items in relation to sexual function showed no diff erences between the 2 groups. Concerning the voiding condition, bladder emptying, frequency, and urgency, scores in the sigmoidal OUR group were signifi cantly higher. The QOL score concerning voiding conditions, daytime, and nighttime continence and quantity of pad showed a better score in the ileal OUR group. Concerning the satisfaction with methods of urinary diversion, patients in the sigmoidal OUR group expressed less satisfaction than their preoperative expectations. Considering several postoperative voiding conditions, ileal OUR seems superior to sigmoidal OUR. |
| Keywords | urinary diversion orthotopic urinary reservoirs bladder cancer quality of life |
| Amo Type | Original Article |
| Published Date | 2007-08 |
| Publication Title | Acta Medica Okayama |
| Volume | volume61 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 229 |
| End Page | 234 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | 英語 |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 17726512 |
| Web of Science KeyUT | 000248957100007 |
| Author | Nasu, Yasutomo| |
|---|---|
| Published Date | 2011-08-01 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume123 |
| Issue | issue2 |
| Content Type | Journal Article |
| JaLCDOI | 10.18926/AMO/52142 |
|---|---|
| FullText URL | 68_1_35.pdf |
| Author | Araki, Motoo| Jeong, Wooju| Park, Sung Yul| Lee, Young Hoon| Nasu, Yasutomo| Kumon, Hiromi| Hong, Sung Joon| Rha, Koon Ho| |
| Abstract | The purpose of this study was to compare the positive surgical margin (PSM) rates of 2 techniques of robot-assisted radical prostatectomy (RARP) for pT2 (localized) prostate cancer. A retrospective analysis was conducted of 361 RARP cases, performed from May 2005 to September 2008 by a single surgeon (KHR) at our institution (Yonsei University College of Medicine). In the conventional technique, the bladder neck was transected first. In the modified ultradissection, the lateral border of the bladder neck was dissected and then the bladder neck was transected while the detrusor muscle of the bladder was well visualized. Perioperative characteristics and outcomes and PSM rates were analyzed retrospectively for pT2 patients (n＝217), focusing on a comparison of those undergoing conventional (n＝113) and modified ultradissection (n＝104) techniques. There was no difference between the conventional and modified ultradissection group in mean age, BMI, PSA, prostate volume, biopsy Gleason score, and DʼAmico prognostic criteria distributions. The mean operative time was shorter (p＜0.001) and the estimated blood loss was less (p＜0.01) in the modified ultradissection group. The PSM rate for the bladder neck was significantly reduced by modified ultradissection, from 6.2% to 0% (p＜0.05). In conclusion, modified ultradissection reduces the PSM rate for the bladder neck. |
| Keywords | robot-assisted radical prostatectomy prostate cancer surgery surgical margin technique |
| Amo Type | Original Article |
| Published Date | 2014-02 |
| Publication Title | Acta Medica Okayama |
| Volume | volume68 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 35 |
| End Page | 41 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | 英語 |
| Copyright Holders | CopyrightⒸ 2014 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 24553487 |
| Web of Science KeyUT | 000331592800006 |
| Title Alternative | Okayama University Hospital as a Clinical Core Hospital |
|---|---|
| FullText URL | 126_231.pdf |
| Author | Nasu, Yasutomo| |
| Keywords | メガホスピタル ICH-GCP 治験 臨床研究 |
| Publication Title | 岡山医学会雑誌 |
| Published Date | 2014-12-01 |
| Volume | volume126 |
| Issue | issue3 |
| Start Page | 231 |
| End Page | 235 |
| ISSN | 0030-1558 |
| language | 日本語 |
| Copyright Holders | Copyright (c) 2014 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.126.231 |
| NAID | 130004903240 |
| JaLCDOI | 10.18926/AMO/60806 |
|---|---|
| FullText URL | 74_5_443.pdf |
| Author | Sekito, Takanori| Araki, Motoo| Hiraki, Takao| Uka, Mayu| Komaki, Toshiyuki| Matsui, Yusuke| Iguchi, Toshihiro| Katayama, Satoshi| Yoshinaga, Kasumi| Watari, Shogo| Maruyama, Yuki| Mitsui, Yosuke| Kubota, Risa| Sadahira, Takuya| Nishimura, Shingo| Wada, Koichiro| Takamoto, Atsushi| Edamura, Kohei| Sako, Tomoko| Kobayashi, Yasuyuki| Watanabe, Toyohiko| Kanazawa, Susumu| Nasu, Yasutomo| |
| Abstract | We report a 47-year-old Japanese female with 10 previous treatments for multiple bilateral renal cell carcinoma (RCC) associated with von Hippel-Lindau disease. The 14-mm right lower pole renal tumor was in contact with the right ureter. Laparoscopic cryoablation was performed to protect the ureter wrapped with gauze. Computed tomography (CT) monitoring was used to confirm the precise ≥ 6 mm ice-ball margin. There was no local progression at 6-months post-surgery. The serum creatinine has been stable. This is apparently the first report of combined laparoscopic and CT monitoring of an ice-ball formation and its margin during cryoablation for RCC. |
| Keywords | laparoscopic cryoablation multiple renal masses nephron-sparing surgery renal cell carcinoma von Hippel-Lindau disease |
| Amo Type | Case Report |
| Note | Fig. 1B is replaced on Dec. 23, 2020.| |
| Published Date | 2020-10 |
| Publication Title | Acta Medica Okayama |
| Volume | volume74 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 443 |
| End Page | 448 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | 英語 |
| Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 33106702 |
| Author | Nasu, Yasutomo| |
|---|---|
| Published Date | 2016-12-01 |
| Publication Title | Journal of Okayama Medical Association |
| Volume | volume128 |
| Issue | issue3 |
| Content Type | Journal Article |
| Author | Sakaguchi, Masakiyo| Kataoka, Ken| Abarzua, Fernando| Tanimoto, Ryuta| Watanabe, Masami| Murata, Hitoshi| Than, Swe Swe| Kurose, Kaoru| Kashiwakura, Yuji| Ochiai, Kazuhiko| Nasu, Yasutomo| Kumon, Hiromi| Huh, Nam-ho| |
|---|---|
| Published Date | 2009-05-22 |
| Publication Title | The Journal of Biological Chemistry |
| Volume | volume284 |
| Issue | issue21 |
| Content Type | Journal Article |
| Author | Hayashi, Tatsuro| Asano, Hiroaki| Toyooka, Shinichi| Tsukuda, Kazunori| Soh, Junichi| Shien, Tadahiko| Taira, Naruto| Maki, Yuho| Tanaka, Norimitsu| Doihara, Hiroyoshi| Nasu, Yasutomo| Huh, Nam-ho| Miyoshi, Shinichiro| |
|---|---|
| Published Date | 2012-05 |
| Publication Title | Journal of Cancer Research and Clinical Oncology |
| Volume | volume138 |
| Issue | issue5 |
| Content Type | Journal Article |
| JaLCDOI | 10.18926/AMO/54976 |
|---|---|
| FullText URL | 71_2_91.pdf |
| Author | Ogawa, Nanako| Sato, Shuhei| Ida, Kentaro| Kato, Katsuya| Ariyoshi, Yuichi| Wada, Koichiro| Nasu, Yasutomo| Kanazawa, Susumu| |
| Abstract | The aim of this study was to investigate the utility of single-source dual-energy computed tomography (SS-DECT) composition analysis in characterizing different types of urinary stones and differentiating them from phleboliths. This study included 29 patients with urinary stones who were scheduled for surgery. All patients were scanned, first using single-energy computed tomography acquisition and then DECT acquisition on SS-DECT. Dual-energy data were archived to a Gemstone spectral imaging (GSI) viewer (GE Healthcare, Milwaukee, WI, USA). Hounsfield units (HU) and effective atomic numbers (Zeff) were estimated using the GSI viewer. The results of dual-energy analysis were compared with the biochemical constitution of the stones. The chemical analysis determined that the stones included 32 calcium-based, 6 cystine and 1 struvite stone. Both HU and Zeff values were helpful in differentiating calcium-based stones from cystine and struvite stones and phleboliths. The Zeff values of phleboliths were significantly higher than those for struvite and cystine stones, whereas it was difficult to distinguish phleboliths from struvite and cystine stones using the HU values. Composition analysis using SS-DECT is helpful for distinguishing urinary stone types and discriminating phleboliths from urinary stones. Zeff values may be more useful than HU values for differentiating urinary stones from phleboliths. |
| Keywords | single-source dual-energy computed tomography effective atomic number urinary stone phlebolith |
| Amo Type | Original Article |
| Published Date | 2017-04 |
| Publication Title | Acta Medica Okayama |
| Volume | volume71 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 91 |
| End Page | 96 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | 英語 |
| Copyright Holders | CopyrightⒸ 2017 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 28420889 |
| JaLCDOI | 10.18926/AMO/30759 |
|---|---|
| FullText URL | fulltext.pdf |
| Author | Kaku, Haruki| Saika, Takashi| Tsushima, Tomoyasu| Nagai, Atsushi| Yokoyama, Teruhiko| Abarzua, Fernando| Ebara, Shin| Manabe, Daisuke| Nasu, Yasutomo| Kumon, Hiromi| |
| Abstract | <p>We evaluated the efficiency and toxicity of estramustine phosphate (ECT), ifosfamide (IFM) and cisplatin (CDDP) combination chemotherapy in twenty-one patients with hormone-refractory prostate cancer (HRPC), for which there is currently no effective treatment. Patients received a daily dose of 560 mg ECT in combination with 1.2 g/m2 IFM on days 1 to 5 and 70 mg/m2 CDDP on day 1. This combination therapy was given every 3 to 4 weeks. An objective response of more than 50% reduction in prostate-specific antigen was observed in 9 of 18 patients (50%), and a more than 50% reduction in bi-dimensionally measurable soft-tissue lesions was observed in 2 of 7 patients (29%). The median duration of response among the cases showing partial response was 40 weeks, while the median duration of response of overall partial-response plus stable cases was 30 weeks. The median survival duration of all cases was 47 weeks. Toxicity was modest and acceptable. In conclusion, the ECT, IFM and CDDP combination chemotherapy regimen is a viable treatment option for HRPC. However, in comparison with our previous chemotherapy regimen of IFM and CDDP, no additional long-lasting effects resulting from the inclusion of ECT could be affirmed.</p> |
| Keywords | hormone-refractory prostate cancer chemotherapy estramustine phosphate ifosfamide cisplatin |
| Amo Type | Article |
| Published Date | 2006-02 |
| Publication Title | Acta Medica Okayama |
| Volume | volume60 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 43 |
| End Page | 49 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | 英語 |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 16508688 |
| Web of Science KeyUT | 000235538900005 |
| JaLCDOI | 10.18926/AMO/31973 |
|---|---|
| FullText URL | fulltext.pdf |
| Author | Edamura, Kohei| Saika, Takashi| Senoh, Takashi| Koizumi, Fumihito| Manabe, Daisuke| Ebara, Shin| Kaku, Haruki| Yokoyama, Teruhiko| Abarzua, Fernando| Nagai, Atsushi| Nasu, Yasutomo| Tsushima, Tomoyasu| Kumon, Hiromi| |
| Abstract | <p>This study was undertaken to reveal the trends of prostate cancer and the outcome of treatment modalities for each disease stage in patients in a single institute over a 10-year period. From January 1994 through December 2003, 420 consecutive patients with previously untreated and histologically confirmed prostate cancer were analyzed for annual distributions of disease stages and treatment modalities and for long-term clinical progression-free survival, prostate cancer-specific survival, and prostate-specific antigen (PSA) failure-free survival rates for each stage and treatment modality. Annual trends showed that the number of patients, especially those with clinically localized cancer, increased dramatically. The 5-year disease-specific survival rates for patients with clinically localized disease were 100 percent for all treatment modalities, including hormonal therapy alone. Patients with PSA levels less than 10 ng/ml showed an 81 percent 5-year PSA failure-free survival rate with radical prostatectomy. Stage C patients treated by surgery or radiation-based therapy with concomitant hormonal therapy obtained 93 percent and 100 percent cause-specific survival rates, respectively, and those treated by hormonal therapy alone showed a 79 percent rate. The number of patients with localized prostate cancer was increasing in this decade. While long-term hormonal therapy alone was highly efficient in controlling localized prostate cancer, radical therapies in conjunction with neo-adjuvant hormonal therapy produced better survival rates in cases of locally advanced disease.</p> |
| Keywords | prostate carcinoma long-term cohort retrospective outcome |
| Amo Type | Article |
| Published Date | 2005-10 |
| Publication Title | Acta Medica Okayama |
| Volume | volume59 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 195 |
| End Page | 199 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | 英語 |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 16286958 |
| Web of Science KeyUT | 000232835600003 |
| JaLCDOI | 10.18926/AMO/32815 |
|---|---|
| FullText URL | fulltext.pdf |
| Author | Saika, Takashi| Tsushima, Tomoyasu| Nasu, Yasutomo| Arata, Ryoji| Kaku, Haruki| Akebi, Naoki| Kusaka, Nobuyuki| Kumon, Hiromi| |
| Abstract | <p>The aim of this study was to reveal the clinical features of anterior urethral recurrence in patients with superficial bladder cancer, and to determine the appropriate treatment. Three hundred and three patients with superficial bladder cancer, who were newly diagnosed and initially treated conservatively in our hospital between 1965 and 1990, were followed for at least 5 years and their clinical outcomes were analyzed. Clinical factors, including anterior urethral recurrence, were evaluated statistically regarding tumor progression. Eight patients (2.6%) had anterior urethral recurrence following superficial bladder cancer. Twenty-four patients (7.9%) had tumor progression and 149 (49.2%) had tumor recurrence. In a multivariate analysis using a logistic model, anterior urethral recurrence was the most important factor, followed by histological grade. Four of 5 patients who were treated for anterior urethral recurrent tumors by transurethral resection showed progression and died of the cancer within one year. Two of the remaining three patients who underwent radical cysto-urethrectomy at the time of anterior urethral recurrence survived. Anterior urethral recurrence following superficial bladder cancer is a predictor for rapid subsequent malignant progression. Once there is anterior urethral recurrence, radical intensive therapy, including radical cysto-urethrectomy, should be carried out immediately.</p> |
| Keywords | superficial bladder cancer anterior urehral recurrence prognosis predictor |
| Amo Type | Article |
| Published Date | 2003-12 |
| Publication Title | Acta Medica Okayama |
| Volume | volume57 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 293 |
| End Page | 297 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | 英語 |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 14726966 |
| Web of Science KeyUT | 000187556500004 |
| JaLCDOI | 10.18926/AMO/32881 |
|---|---|
| FullText URL | fulltext.pdf |
| Author | Murakami, Takanori| Ebara, Shin| Saika, Takashi| Irie, Shin| Takeda, Katsuji| Maki, Yoshio| Miyaji, Sadayuki| Manabe, Daisuke| Kaku, Haruki| Nasu, Yasutomo| Tsushima, Tomoyasu| Kumon, Hiromi| |
| Abstract | <p>We evaluated the need for transurethral biopsy at first follow-up after intravesical bacillus Calmette-Guerin (BCG) therapy for superficial bladder cancer. The records of 84 patients with superficial bladder cancer who received a 6- or 8-week course of BCG were reviewed. Pathological results before BCG, cystoscopic findings, urinary cytology, and biopsy results for evaluation of BCG therapy were reviewed. All 19 patients with positive urinary cytology had evidence of positive bladder biopsy results. Fifty-three of 54 patients (98.1%) with no visible recurrent tumor and negative urinary cytology demonstrated negative pathological results on bladder biopsy. When not found in conjunction with positive urinary cytology, erythematous mucosa on cystoscopy was not an indicator of tumor recurrence or residual cancer. In conclusion, routine transurethral biopsy of the bladder for evaluating the response to BCG intravesical therapy is not necessary in patients who have no visible tumor on cystoscopy and negative urinary cytology./</p> |
| Keywords | bladder cancer BCG therapy transurethral biopsy cystoscopy urinary cytology |
| Amo Type | Original Article |
| Published Date | 2007-12 |
| Publication Title | Acta Medica Okayama |
| Volume | volume61 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 341 |
| End Page | 344 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | 英語 |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 18183079 |
