Nojima, Tsuyoshi - OU Author List - OKAYAMA UNIVERSITY SCIENTIFIC ACHIEVEMENT REPOSITORY

Organ Donation after Extracorporeal Cardiopulmonary Resuscitation: Clinical and Ethical Perspectives

JaLCDOI	10.18926/AMO/69147
FullText URL	79_4_221.pdf
Author	Yumoto, Tetsuya\| Naito, Hiromichi\| Hongo, Takashi\| Obara, Takafumi\| Kosaki, Yoshinori\| Ageta, Kohei\| Nojima, Tsuyoshi\| Tsukahara, Kohei\| Nakao, Atsunori\|
Abstract	Extracorporeal cardiopulmonary resuscitation (ECPR) has evolved into a life-saving therapy for select cardiac arrest patients, yet a growing body of evidence suggests it also holds promise as a bridge to organ donation in non-survivors. This review explores the clinical outcomes, ethical complexities, and evolving policies surrounding organ donation after ECPR. We summarize recent international and Japanese data demonstrating favorable graft function from ECPR donors, with the exception of lung transplantation. The ethical challenges — particularly those involving brain death determination on extracorporeal membrane oxygenation and adherence to the dead donor rule — are discussed in the context of Japan’s recent regulatory reforms. Additionally, we highlight the importance of structured end-of-life communication through multidisciplinary team meetings in facilitating ethically sound transitions from rescue efforts to donation pathways. Moving forward, improvements in donor management, standardized legal frameworks, and public and professional education are essential to optimizing the life-saving and life-giving potential of ECPR.
Keywords	brain death end-of-life care ethical dilemmas extracorporeal cardiopulmonary resuscitation
Amo Type	Review
Publication Title	Acta Medica Okayama
Published Date	2025-08
Volume	volume79
Issue	issue4
Publisher	Okayama University Medical School
Start Page	221
End Page	229
ISSN	0386-300X
NCID	AA00508441
Content Type	Journal Article
language	English
Copyright Holders	Copyright Ⓒ 2025 by Okayama University Medical School
File Version	publisher
Refereed	True

Association of emergency intensive care unit occupancy due to brain-dead organ donors with ambulance diversion

FullText URL	fulltext.pdf
Author	Yumoto, Tetsuya\| Obara, Takafumi\| Hongo, Takashi\| Nojima, Tsuyoshi\| Tsukahara, Kohei\| Hisamura, Masaki\| Nakao, Atsunori\| Yorifuji, Takashi\| Naito, Hiromichi\|
Keywords	Ambulance diversion Bed occupancy Brain death Emergency medical services Intensive care units Organ donation
Published Date	2025-04-12
Publication Title	Scientific Reports
Volume	volume15
Issue	issue1
Publisher	Nature Portfolio
Start Page	12633
ISSN	2045-2322
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2025
File Version	publisher
PubMed ID	40221631
DOI	10.1038/s41598-025-97198-7
Web of Science KeyUT	001466042000027
Related Url	isVersionOf https://doi.org/10.1038/s41598-025-97198-7

Association of blood carboxyhemoglobin levels with mortality and neurological outcomes in out-of-hospital cardiac arrest

FullText URL	fulltext.pdf
Author	Hongo, Takashi\| Yumoto, Tetsuya\| Naito, Hiromichi\| Hiraoka, Tomohiro\| Murakami, Yuya\| Obara, Takafumi\| Nojima, Tsuyoshi\| Aokage, Toshiyuki\| Nakao, Atsunori\|
Keywords	brain injury carbon monoxide carboxyhemoglobin cardiac arrest resuscitation
Published Date	2025-03-23
Publication Title	Acute Medicine & Surgery
Volume	volume12
Issue	issue1
Publisher	Wiley
Start Page	e70053
ISSN	2052-8817
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2025 The Author(s).
File Version	publisher
PubMed ID	40130086
DOI	10.1002/ams2.70053
Web of Science KeyUT	001450042700001
Related Url	isVersionOf https://doi.org/10.1002/ams2.70053

Transversal Survey of Emergency Medicine Policy and Quality Metrics in Japan' s Regional Health Care Plans

FullText URL	fulltext.pdf
Author	Iida, Atsuyoshi\| Saito, Shinya\| Hamada, Jun\| Nakamura, Shunsuke\| Nojima, Tsuyoshi\| Naito, Hiromichi\| Mikane, Takeshi\|
Keywords	emergency medicine indicator measure quality assurance quality improvement
Published Date	2023
Publication Title	JMA Journal
Volume	volume6
Issue	issue3
Publisher	Japan Medical Association
Start Page	284
End Page	291
ISSN	2433-3298
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© Japan Medical Association
File Version	publisher
PubMed ID	37560366
DOI	10.31662/jmaj.2022-0172
Web of Science KeyUT	001163814800013
Related Url	isVersionOf https://doi.org/10.31662/jmaj.2022-0172

A nationwide longitudinal survey of infantile injury and its recurrence in Japan

FullText URL	fulltext.pdf
Author	Hiraoka, Tomohiro\| Obara, Takafumi\| Matsumoto, Naomi\| Tsukahara, Kohei\| Hongo, Takashi\| Nojima, Tsuyoshi\| Hisamura, Masaki\| Yumoto, Tetsuya\| Nakao, Atsunori\| Yorifuji, Takashi\| Naito, Hiromichi\|
Keywords	Retrospective cohort study Injury recurrence Injury prevention
Note	The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-024-76403-z\|
Published Date	2024-10-21
Publication Title	Scientific Reports
Volume	volume14
Issue	issue1
Publisher	Nature Portfolio
Start Page	24716
ISSN	2045-2322
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2024
File Version	publisher
PubMed ID	39433855
DOI	10.1038/s41598-024-76403-z
Web of Science KeyUT	001339991400047
Related Url	isVersionOf https://doi.org/10.1038/s41598-024-76403-z

Organ donation after extracorporeal cardiopulmonary resuscitation: a nationwide retrospective cohort study

FullText URL	fulltext.pdf
Author	Yumoto, Tetsuya\| Tsukahara, Kohei\| Obara, Takafumi\| Hongo, Takashi\| Nojima, Tsuyoshi\| Naito, Hiromichi\| Nakao, Atsunori\|
Keywords	Brain death Cardiopulmonary resuscitation Extracorporeal membrane oxygenation Organ transplantation Out-of-hospital cardiac arrest Tissue and organ procurement
Note	The version of record of this article, first published in Critical Care, is available online at Publisher’s website: http://dx.doi.org/10.1186/s13054-024-04949-5\|
Published Date	2024-05-13
Publication Title	Critical Care
Volume	volume28
Issue	issue1
Publisher	BMC
Start Page	160
ISSN	1364-8535
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2024.
File Version	publisher
PubMed ID	38741176
DOI	10.1186/s13054-024-04949-5
Web of Science KeyUT	001221675100001
Related Url	isVersionOf https://doi.org/10.1186/s13054-024-04949-5

Schmorl's Node Found with Acute Lower Back Pain

FullText URL	fulltext.pdf
Author	Aoshima, Kenji\| Obara, Takafumi\| Nojima, Tsuyoshi\| Nakao, Atsunori\|
Keywords	Schmorl's node acute back pain intravertebral disc herniations
Published Date	2024-03-01
Publication Title	Internal Medicine
Volume	volume63
Issue	issue5
Publisher	Japanese Society of Internal Medicine
Start Page	759
End Page	760
ISSN	0918-2918
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2024 The Japanese Society of Internal Medicine
File Version	publisher
PubMed ID	37407455
DOI	10.2169/internalmedicine.2203-23
Web of Science KeyUT	001179795300001
Related Url	isVersionOf https://doi.org/10.2169/internalmedicine.2203-23

Hydrogen in Transplantation: Potential Applications and Therapeutic Implications

FullText URL	fulltext.pdf
Author	Obara, Takafumi\| Naito, Hiromichi\| Nojima, Tsuyoshi\| Hirayama, Takahiro\| Hongo, Takashi\| Ageta, Kohei\| Aokage, Toshiyuki\| Hisamura, Masaki\| Yumoto, Tetsuya\| Nakao, Atsunori\|
Keywords	hydrogen organ transplantation ischemia reperfusion
Published Date	2024-01-06
Publication Title	Biomedicines
Volume	volume12
Issue	issue1
Publisher	MDPI
Start Page	118
ISSN	2227-9059
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2024 by the authors.
File Version	publisher
PubMed ID	38255223
DOI	10.3390/biomedicines12010118
Web of Science KeyUT	001149475800001
Related Url	isVersionOf https://doi.org/10.3390/biomedicines12010118

Treatment patterns and clinician stress related to care of out-of-hospital cardiac arrest patients with a do not attempt resuscitation order

FullText URL	fulltext.pdf
Author	Tanabe, Ryo\| Hongo, Takashi\| Obara, Takafumi\| Nojima, Tsuyoshi\| Nakao, Atsunori\| Elmer, Jonathan\| Naito, Hiromichi\| Yumoto, Tetsuya\|
Keywords	Do not attempt resuscitation Out-of-hospital cardiac arrest Emergency department Clinicians Slow code Stress
Published Date	2023-12
Publication Title	Resuscitation Plus
Volume	volume16
Publisher	Elsevier
Start Page	100507
ISSN	2666-5204
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2023 The Author(s).
File Version	publisher
PubMed ID	38026140
DOI	10.1016/j.resplu.2023.100507
Web of Science KeyUT	001112320800001
Related Url	isVersionOf https://doi.org/10.1016/j.resplu.2023.100507

Transmural necrosis of the ascending colon secondary to traumatic hemorrhagic shock: A case report

FullText URL	fulltext.pdf
Author	Aoshima, Kenji\| Yumoto, Tetsuya\| Nojima, Tsuyoshi\| Nakao, Atsunori\| Naito, Hiromichi\|
Keywords	Trauma Hemorrhagic shock Non-occlusive mesenteric ischemia Laparoscopy Case report
Published Date	2023-06
Publication Title	Journal of Pediatric Surgery Case Reports
Volume	volume93
Publisher	Elsevier
Start Page	102646
ISSN	2213-5766
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2023 The Authors.
File Version	publisher
DOI	10.1016/j.epsc.2023.102646
Web of Science KeyUT	000986947200001
Related Url	isVersionOf https://doi.org/10.1016/j.epsc.2023.102646

Hydrogen inhalation attenuates lung contusion after blunt chest trauma in mice

FullText URL	fulltext.pdf
Author	Ageta, Kohei\| Hirayama, Takahiro\| Aokage, Toshiyuki\| Seya, Mizuki\| Meng, Ying\| Nojima, Tsuyoshi\| Yamamoto, Hirotsugu\| Obara, Takafumi\| Nakao, Atsunori\| Yumoto, Tetsuya\| Tsukahara, Kohei\| Naito, Hiromichi\|
Published Date	2023-08
Publication Title	Surgery
Volume	volume174
Issue	issue2
Publisher	Elsevier
Start Page	343
End Page	349
ISSN	0039-6060
NCID	AA00853880
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2023 The Author(s).
File Version	publisher
PubMed ID	37210236
DOI	10.1016/j.surg.2023.04.029
Web of Science KeyUT	001051321100001
Related Url	isVersionOf https://doi.org/10.1016/j.surg.2023.04.029

Hydrogen gas treatment improves survival in a rat model of crush syndrome by ameliorating rhabdomyolysis

FullText URL	fulltext.pdf
Author	Yumoto, Tetsuya\| Aokage, Toshiyuki\| Hirayama, Takahiro\| Yamamoto, Hirotsugu\| Obara, Takafumi\| Nojima, Tsuyoshi\| Naito, Hiromichi\| Nakao, Atsunori\|
Keywords	Crush syndrome experimental model hydrogen ischemia reperfusion injury
Published Date	2023-03-29
Publication Title	European Journal of Inflammation
Volume	volume21
Publisher	SAGE Publications
ISSN	1721-727X
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2023
File Version	publisher
DOI	10.1177/1721727X231168547
Web of Science KeyUT	000960493900001
Related Url	isVersionOf https://doi.org/10.1177/1721727X231168547

Successfully treated case of severe hypothermia secondary to myxedema coma

FullText URL	fulltext.pdf
Author	Yamamoto, Hirotsugu\| Hongo, Takashi\| Nojima, Tsuyoshi\| Obara, Takafumi\| Kosaki, Yoshinori\| Ageta, Kohei\| Tsukahara, Kohei\| Yumoto, Tetsuya\| Nakao, Atsunori\| Naito, Hiromichi\|
Keywords	Cardiac arrest diagnosis hypothermia hypothyroidism myxedema coma
Published Date	2023-03-14
Publication Title	Acute Medicine and Surgery
Volume	volume10
Issue	issue1
Publisher	Wiley
Start Page	e828
ISSN	2052-8817
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2023 The Authors.
File Version	publisher
PubMed ID	36936740
DOI	10.1002/ams2.828
Web of Science KeyUT	000949262800001
Related Url	isVersionOf https://doi.org/10.1002/ams2.828

Luminal administration of biliverdin ameliorates ischemia-reperfusion injury following intestinal transplant in rats

FullText URL	fulltext20221122-1.pdf
Author	Nojima, Tsuyoshi\| Obara, Takafumi\| Yamamoto, Hirotsugu\| Yumoto, Tetsuya\| Igawa, Takuro\| Aokage, Toshiyuki\| Seya, Mizuki\| Nakao, Atsunori\| Naito, Hiromichi\|
Published Date	2022-11
Publication Title	Surgery
Volume	volume172
Issue	issue5
Publisher	Elsevier BV
Start Page	1522
End Page	1528
ISSN	0039-6060
NCID	AA00853880
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2022 The Author(s)
File Version	publisher
PubMed ID	36088170
DOI	10.1016/j.surg.2022.07.021
Web of Science KeyUT	000875983900035
Related Url	isVersionOf https://doi.org/10.1016/j.surg.2022.07.021

Bile pigments in emergency and critical care medicine

FullText URL	fulltext.pdf
Author	Seya, Mizuki\| Aokage, Toshiyuki\| Nojima, Tsuyoshi\| Nakao, Atsunori\| Naito, Hiromichi\|
Keywords	Bile pigments Emergency and critical care medicine Antioxidant therapy
Published Date	2022-10-29
Publication Title	European Journal Of Medical Research
Volume	volume27
Issue	issue1
Publisher	BMC
Start Page	224
ISSN	0949-2321
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2022.
File Version	publisher
PubMed ID	36309733
DOI	10.1186/s40001-022-00863-0
Web of Science KeyUT	000876312700004
Related Url	isVersionOf https://doi.org/10.1186/s40001-022-00863-0

Adult Scurvy Presenting with Painful Purpura on the Legs

FullText URL	fulltext.pdf
Author	Tamura, Nayu\| Obara, Takafumi\| Yamada, Taihei\| Nojima, Tsuyoshi\| Nakamura, Shunsuke\| Koide, Yasuhiro\| Takaoka, Makoto\| Naito, Hiromichi\| Nakao, Atsunori\|
Keywords	vitamin C malnutrition malabsorption peliosis anemia
Published Date	2022
Publication Title	Internal Medicine
Volume	volume61
Issue	issue12
Publisher	The Japanese Society of Internal Medicine
Start Page	1913
End Page	1916
ISSN	0918-2918
NCID	AA12022491
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2022 The Japanese Society of Internal Medicine
File Version	publisher
PubMed ID	34776490
DOI	10.2169/internalmedicine.8409-21
Web of Science KeyUT	000813840600001
Related Url	isVersionOf https://doi.org/10.2169/internalmedicine.8409-21

Mid-term (30- to 90-day) neurological changes in out-of-hospital cardiac arrest patients: A nationwide retrospective study (the JAAM-OHCA registry)

FullText URL	fulltext20220630-9.pdf
Author	Naito, Hiromichi\| Nojima, Tsuyoshi\| Yorifuji, Takashi\| Fujisaki, Noritomo\| Nakao, Atsunori\|
Keywords	Post cardiac arrest syndrome Hypoxic ischemic brain injury Cardiopulmonary resuscitation Prognosis
Published Date	2022-8
Publication Title	The American Journal of Emergency Medicine
Volume	volume58
Publisher	Elsevier BV
Start Page	27
End Page	32
ISSN	0735-6757
NCID	AA10642870
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2022 The Authors.
File Version	publisher
PubMed ID	35623180
DOI	10.1016/j.ajem.2022.05.017
Web of Science KeyUT	000808614800006

Prehospital emergency life-saving technicians promote the survival of trauma patients: A retrospective cohort study

FullText URL	fulltext20220630-8.pdf
Author	Nishimura, Takeshi\| Nojima, Tsuyoshi\| Naito, Hiromichi\| Ishihara, Satoshi\| Nakayama, Shinichi\| Nakao, Atsunori\|
Keywords	JTDB Prehospital Emergency life-saving technician Trauma
Published Date	2022-06
Publication Title	The American Journal of Emergency Medicine
Volume	volume56
Publisher	Elsevier BV
Start Page	218
End Page	222
ISSN	0735-6757
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2022 The Authors.
File Version	publisher
PubMed ID	35447563
DOI	10.1016/j.ajem.2022.04.004
Web of Science KeyUT	000799775900035
Related Url	isVersionOf https://doi.org/10.1016/j.ajem.2022.04.004

Can Blood Ammonia Level, Prehospital Time, and Return of Spontaneous Circulation Predict Neurological Outcomes of Out-of-Hospital Cardiac Arrest Patients? A Nationwide, Retrospective Cohort Study

FullText URL	fulltext.pdf
Author	Nojima, Tsuyoshi\| Naito, Hiromichi\| Obara, Takafumi\| Ageta, Kohei\| Yakushiji, Hiromasa\| Yumoto, Tetsuya\| Fujisaki, Noritomo\| Nakao, Atsunori\|
Keywords	ammonia cardiopulmonary resuscitation neurological outcome biomarkers
Published Date	2022-05-04
Publication Title	Journal Of Clinical Medicine
Volume	volume11
Issue	issue9
Publisher	MDPI
Start Page	2566
ISSN	2077-0383
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2022 by the authors.
File Version	publisher
PubMed ID	35566692
DOI	10.3390/jcm11092566
Web of Science KeyUT	000794498600001
Related Url	isVersionOf https://doi.org/10.3390/jcm11092566

Refractory gastric ulcer due to undisclosed use of topical diclofenac epolamine patches

FullText URL	fulltext.pdf
Author	Oda, Yuta\| Naito, Hiromichi\| Nojima, Tsuyoshi\| Nakao, Atsunori\|
Keywords	Gastric ulcer topical nonsteroidal anti-inflammatory drug
Published Date	2021-11-20
Publication Title	Acute Medicine & Surgery
Volume	volume8
Issue	issue1
Publisher	Wiley
Start Page	e710
ISSN	2052-8817
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2021 The Authors.
File Version	publisher
DOI	10.1002/ams2.710
Web of Science KeyUT	000720628700001
Related Url	isVersionOf https://doi.org/10.1002/ams2.710