| Title Alternative | Synthetic studies of ancistrocladinium A and B, antileishmanial compounds isolated from a Congolese Ancistrocladus Species |
|---|---|
| FullText URL | srfa_108_001_004.pdf |
| Author | Kiyota, Hiromasa| Saito, Akihito| Takai, Momoko| Kuwahara, Shigefumi| |
| Abstract | Synthetic studies of ancistrocladinium A and B, antileishmanial compounds isolated from a Congolese Ancistrocladus sp., are described. Buchwald‒Hartwig coupling reaction between the dihydroisoquinoline and the naphthyl triflate failed. The main framework of ancistrocladinium A was constructed by 1,2‒addition of the amine to the naphthoquinone in the presence of celium trichloride as a catalyst. On the other hand, 1,4‒addition of the amine to the naphthoquinone proceeded without catalyst to form the framework of B. These products will be valuable leads for antileishmanial agents. |
| Keywords | ancistrocladinium A and B synthetic studies leishmania, Ancistrocladus isoquinoline |
| Publication Title | Scientific Reports of the Faculty of Agriculture, Okayama University |
| Published Date | 2019-02-01 |
| Volume | volume108 |
| Start Page | 1 |
| End Page | 4 |
| ISSN | 2186-7755 |
| language | 日本語 |
| File Version | publisher |
| FullText URL | Sci_Rep_15_7_8239.pdf |
|---|---|
| Author | Vavrick, Christopher J.| Muto, Chiaki| Hasunuma, Tomohisa| Kimura, Yoshinobu| Araki, Michihiro| Wu, Yan| Gao, George F.| Ohrui, Hiroshi| Izumi, Minoru| Kiyota, Hiromasa| |
| Note | This is an article published by Science| |
| Published Date | 2017-08 |
| Publication Title | Scientific Reports |
| Volume | volume7 |
| Issue | issue1 |
| Publisher | Nature Publishing Group |
| Start Page | 8239 |
| ISSN | 2045-2322 |
| Content Type | Journal Article |
| language | 英語 |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja |
| File Version | publisher |
| PubMed ID | 28811524 |
| DOI | 10.1038/s41598-017-07836-y |
| Web of Science KeyUT | 000407570000116 |
| Related Url | https://doi.org/10.1038/s41598-017-07836-y |
| FullText URL | 17P-SO3-Sia-SR.pdf |
|---|---|
| Author | Vavricka, Christopher J.| Muto, Chiaki| Hasunuma, Tomohisa| Kimura, Yoshinobu| Araki, Michihiro| Wu, Yan| Gao, George F.| Ohrui, Hiroshi| Izumi, Minoru| Kiyota, Hiromasa| |
| Keywords | Antiviral agents Drug discovery and development Glycosides |
| Published Date | 2017-08 |
| Publication Title | Scientific Reports |
| Volume | volume7 |
| Issue | issue1 |
| Publisher | Nature Publishing Group |
| Start Page | 8239 |
| ISSN | 2045-2322 |
| Content Type | Journal Article |
| language | 英語 |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja |
| File Version | publisher |
| PubMed ID | 28811524 |
| DOI | 10.1038/s41598-017-07836-y |
| Web of Science KeyUT | 000407570000116 |
| Related Url | https://doi.org/10.1038/s41598-017-07836-y |
| Author | Kiyota, Hiromasa| |
|---|---|
| Published Date | 2017-02-01 |
| Publication Title | Scientific Reports of the Faculty of Agriculture, Okayama University |
| Volume | volume106 |
| Content Type | Departmental Bulletin Paper |
| Author | Wu, Yi-Bing| Liu, Dan| Liu, Pei-Yu| Yang, Xue-Mei| Liao, Man| Lu, Nan-Nan| Sauriol, FranÅoise| Gu, Yu-Cheng| Shi, Qing-Wen| Kiyota, Hiromasa| Dong, Mei| |
|---|---|
| Published Date | 2015-05-26 |
| Publication Title | Helvetica Chimica Acta |
| Volume | volume98 |
| Issue | issue5 |
| Content Type | Journal Article |
