Author Kitagawa, Masashi| Sugiyama, Hitoshi| Morinaga, Hiroshi| Inoue, Tatsuyuki| Takiue, Keiichi| Ogawa, Ayu| Yamanari, Toshio| Kikumoto, Yoko| Uchida, Haruhito Adam| Kitamura, Shinji| Maeshima, Yohei| Nakamura, Kazufumi| Ito, Hiroshi| Makino, Hirofumi|
Published Date 2013-02-19
Publication Title PLoS ONE
Volume volume8
Issue issue2
Content Type Journal Article
FullText URL fulltext.pdf
Author Takaya, Yoichi| Akagi, Teiji| Nakagawa, Koji| Nakayama, Rie| Miki, Takashi| Watanabe, Nobuhisa| Toh, Norihisa| Ito, Hiroshi|
Published Date 2020-03-03
Publication Title Journal of Interventional Cardiology
Volume volume2020
Publisher Hindawi
Start Page 6090612
ISSN 0896-4327
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © 2020 Yoichi Takaya et al.
File Version publisher
PubMed ID 32206044
DOI 10.1155/2020/6090612
Web of Science KeyUT 000522373900001
Related Url isVersionOf https://doi.org/10.1155/2020/6090612
FullText URL fulltext.pdf
Author Yoshida, Masatoki| Nakamura, Kazufumi| Miyoshi, Toru| Yoshida, Masashi| Kondo, Megumi| Akazawa, Kaoru| Kimura, Tomonari| Ohtsuka, Hiroaki| Ohno, Yuko| Miura, Daiji| Ito, Hiroshi|
Keywords Pemafibrate Statin Endothelial function
Note The Correction to this article has been published in Cardiovascular Diabetology 2020 19:213. https://doi.org/10.1186/s12933-020-01181-7.|
Published Date 2020-09-26
Publication Title Cardiovascular Diabetology
Volume volume19
Issue issue1
Publisher BMC
Start Page 149
ISSN 1475-2840
NCID AA12050431
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders Ⓒ Author(s)
File Version publisher
PubMed ID 32979918
DOI 10.1186/s12933-020-01132-2
Web of Science KeyUT 000576188900001
Related Url isVersionOf https://doi.org/10.1186/s12933-020-01132-2
FullText URL fulltext.pdf
Author Yoshida, Masatoki| Nakamura, Kazufumi| Miyoshi, Toru| Yoshida, Masashi| Kondo, Megumi| Akazawa, Kaoru| Kimura, Tomonari| Ohtsuka, Hiroaki| Ohno, Yuko| Miura, Daiji| Ito, Hiroshi|
Note Correction to: Cardiovasc Diabetol (2020) 19:149 https://doi.org/10.1186/s12933-020-01132-2 |
Published Date 2020-12-14
Publication Title Cardiovascular Diabetology
Volume volume19
Issue issue1
Publisher BMC
Start Page 213
ISSN 1475-2840
NCID AA12050431
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2020.
File Version publisher
PubMed ID 33317516
DOI 10.1186/s12933-020-01181-7
Web of Science KeyUT 000599850200001
Related Url isVersionOf https://doi.org/10.1186/s12933-020-01181-7
FullText URL fulltext.pdf
Author Nakamura, Kazufumi| Akagi, Satoshi| Ejiri, Kentaro| Yoshida, Masashi| Miyoshi, Toru| Toh, Norihisa| Nakagawa, Koji| Takaya, Yoichi| Matsubara, Hiromi| Ito, Hiroshi|
Keywords pulmonary arterial hypertension prostaglandin I-2 nitric oxide endothelin
Published Date 2019-11-23
Publication Title International Journal of Molecular Sciences
Volume volume20
Issue issue23
Publisher MDPI
Start Page 5885
ISSN 1422-0067
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © 2019 by the authors.
File Version publisher
PubMed ID 31771203
DOI 10.3390/ijms20235885
Web of Science KeyUT 000504428300067
Related Url isVersionOf https://doi.org/10.3390/ijms20235885
FullText URL fulltext.pdf
Author Hatipoglu, Omer F.| Miyoshi, Toru| Yonezawa, Tomoko| Kondo, Megumi| Amioka, Naofumi| Yoshida, Masashi| Akagi, Satoshi| Nakamura, Kazufumi| Hirohata, Satoshi| Ito, Hiroshi|
Keywords Aneurysm Aortic diseases
Published Date 2020-04-22
Publication Title Scientific Reports
Volume volume10
Issue issue1
Publisher Nature
Start Page 6869
ISSN 2045-2322
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2020
File Version publisher
PubMed ID 32321956
DOI 10.1038/s41598-020-63824-9
Web of Science KeyUT 000560329100004
Related Url isVersionOf https://doi.org/10.1038/s41598-020-63824-9
Author Kobayashi, Junko| Yoshida, Masashi| Tarui, Suguru| Hirata, Masataka| Nagai, Yusuke| Kasahara, Shingo| Naruse, Keiji| Ito, Hiroshi| Sano, Shunji| Oh, Hidemasa|
Published Date 2014-07-22
Publication Title PLoS ONE
Volume volume9
Issue issue7
Content Type Journal Article
Author Wada, Tadashi| Nakahama, Makoto| Toda, Hironobu| Watanabe, Atsuyuki| Hashimoto, Katsushi| Terasaka, Ritsuko| Nakamura, Kazufumi| Yamada, Nobuyuki| Ito, Hiroshi|
Published Date 2013
Publication Title ISRN Cardiology
Volume volume2013
Content Type Journal Article
FullText URL fulltext.pdf
Author Ejiri, Kentaro| Miyoshi, Toru| Kihara, Hajime| Hata, Yoshiki| Nagano, Toshihiko| Takaishi, Atsushi| Toda, Hironobu| Nanba, Seiji| Nakamura, Yoichi| Akagi, Satoshi| Sakuragi, Satoru| Minagawa, Taro| Kawai, Yusuke| Nishii, Nobuhiro| Fuke, Soichiro| Yoshikawa, Masaki| Nakamura, Kazufumi| Ito, Hiroshi|
Keywords B-type natriuretic peptide diabetes mellitus heart failure sodium-glucose cotransporter 2 inhibitor
Published Date 2020-08-18
Publication Title Journal of the American Heart association
Volume volume9
Issue issue16
Publisher Wiley
Start Page e015103
ISSN 2047-9980
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © 2020 The Authors.
File Version publisher
PubMed ID 32805185
DOI 10.1161/JAHA.119.015103
Web of Science KeyUT 000574868200036
Related Url isVersionOf https://doi.org/10.1161/JAHA.119.015103
FullText URL fulltext.pdf
Author Saito, Yukihiro| Nakamura, Kazufumi| Ito, Hiroshi|
Keywords eicosapentaenoic acid atherosclerosis Klotho
Published Date 2020-07-30
Publication Title International Journal of Molecular Sciences
Volume volume21
Issue issue15
Publisher MDPI
Start Page 5455
ISSN 1422-0067
NCID AA12038549
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © 2020 by the authors.
File Version publisher
PubMed ID 32751754
DOI 10.3390/ijms21155455
Web of Science KeyUT 000559183100001
Related Url isVersionOf https://doi.org/10.3390/ijms21155455
Author Tokioka, Koji| Kusano, Kengo F.| Morita, Hiroshi| Miura, Daiji| Nishii, Nobuhiro| Nagase, Satoshi| Nakamura, Kazufumi| Kohno, Kunihisa| Ito, Hiroshi| Ohe, Tohru|
Published Date 2014-05-27
Publication Title Journal of the American College of Cardiology
Volume volume63
Issue issue20
Content Type Journal Article
JaLCDOI 10.18926/AMO/53519
FullText URL 69_3_129.pdf
Author Akagi, Satoshi| Nakamura, Kazufumi| Matsubara, Hiromi| Ogawa, Aiko| Sarashina, Toshihiro| Ejiri, Kentaro| Ito, Hiroshi|
Abstract Pulmonary arterial hypertension (PAH) is characterized by elevation of pulmonary artery pressure caused by pulmonary vasoconstriction and vascular remodeling, which leads to right heart failure and death. Epoprostenol (prostaglandin I2) has a potent short-acting vasodilator property, and intravenous continuous epoprostenol is therefore used for treatment of PAH. Here we review evidence for the usefulness of intravenous continuous epoprostenol therapy in patients with PAH. Epoprostenol therapy is effective in idiopathic PAH patients and in patients with PAH associated with connective tissue disease, portal hypertension or congenital heart diseases, but it is not effective in patients with pulmonary veno-occlusive disease or pulmonary capillary hemangiomatosis. High-dose epoprostenol therapy markedly improved hemodynamics in some patients with PAH, possibly due to reverse remodeling of pulmonary arteries. This therapy has several side effects and complications such as headache, hypotension and catheter-related infections. Intravenous continuous epoprostenol is an effective treatment, but there are still some problems to be resolved.
Keywords pulmonary arterial hypertension epoprostenol high-dose complications side effects
Amo Type Review
Published Date 2015-06
Publication Title Acta Medica Okayama
Volume volume69
Issue issue3
Publisher Okayama University Medical School
Start Page 129
End Page 136
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
Copyright Holders CopyrightⒸ 2015 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 26101188
Web of Science KeyUT 000356903000001
JaLCDOI 10.18926/AMO/54600
FullText URL 70_5_397.pdf
Author Akagi, Satoshi| Nakamura, Kazufumi| Akagi, Teiji| Nakagawa, Koji| Takaya, Yoichi| Sarashina, Toshihiro| Ejiri, Kentaro| Ito, Hiroshi|
Abstract A treatment strategy for patients with pulmonary hypertension (PH) and atrial septal defect (ASD) remains unclear. This study was designed to evaluate the effects of initial repair of ASD followed by treatment with PH-specific drugs in patients with PH and ASD. Eligible patients receive transcatheter ASD closure followed by treatment with bosentan and sildenafil. Right heart catheterization is performed at baseline and at 12, 24 and 48 weeks. The primary endpoint is change in pulmonary artery pressure and pulmonary vascular resistance from baseline to follow-up. This study should provide valuable information to establish a therapeutic strategy for PH and ASD.
Keywords pulmonary hypertension atrial septal defect repair and treat transcatheter closure
Amo Type Clinical Study Protocols
Published Date 2016-10
Publication Title Acta Medica Okayama
Volume volume70
Issue issue5
Publisher Okayama University Medical School
Start Page 397
End Page 400
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
Copyright Holders CopyrightⒸ 2016 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 27777434
Web of Science KeyUT 000388098700011
Author Dan, Kazuhiro| Miyoshi, Toru| Ueeda, Masayuki| Ohtsuka, Hiroaki| Ugawa, Satoko| Ohnishi, Nobuhiko| Takaishi, Atsushi| Nakamura, Kazufumi| Kusano, Kengo| Ito, Hiroshi|
Published Date 2012-09
Publication Title Circulation Journal
Volume volume76
Issue issue9
Content Type Journal Article
FullText URL fulltext.pdf
Author Nakayama, Rie| Takaya, Yoichi| Akagi, Teiji| Nakagawa, Koji| Watanabe, Nobuhisa| Nobusada, Saori| Matsushita, Toshi| Toh, Norihisa| Kanazawa, Susumu| Ito, Hiroshi|
Published Date 2020-04-28
Publication Title Journal of Interventional Cardiology
Volume volume2020
Publisher Hindawi
Start Page 9509105
ISSN 0896-4327
NCID AA10705096
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © 2020 Rie Nakayama et al.
File Version publisher
PubMed ID 32410917
DOI 10.1155/2020/9509105
Web of Science KeyUT 000533371500001
Related Url isVersionOf https://doi.org/10.1155/2020/9509105
FullText URL fulltext.pdf
Author Ejiri Kentaro| Akagi, Satoshi| Nakamura, Kazufumi| Amioka, Naofumi| Ichikawa, Keishi| Yagi, Takahito| Ito, Hiroshi|
Keywords Rendu-Osler-Weber syndrome arteriovenous malformation pulmonary haemorrhage
Published Date 2019-12-18
Publication Title Pulmonary Circulation
Volume volume9
Issue issue4
Publisher SAGE Publications Inc
ISSN 2045-8932
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2019.
File Version publisher
PubMed ID 31903186
DOI 10.1177/2045894019896677
Web of Science KeyUT 000503484500001
Related Url isVersionOf https://doi.org/10.1177/2045894019896677
FullText URL fulltext.pdf
Author Akagi, Satoshi| Matsubara, Hiromi| Nakamura, Kazufumi| Oto, Takahiro| Ejiri, Kentaro| Ito, Hiroshi|
Keywords Lung transplantation Pulmonary artery hypertension Pulmonary artery pressure Survival
Published Date 2020-01-24
Publication Title Circulation Journal
Volume volume84
Issue issue2
Publisher The Japanese Circulation Society
Start Page 245
End Page 251
ISSN 1346-9843
NCID AA11591968
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
File Version publisher
DOI 10.1253/circj.CJ-19-0784
Related Url isVersionOf https://doi.org/10.1253/circj.CJ-19-0784
FullText URL fulltext.pdf
Author Ogura, Soichiro| Nakamura, Kazufumi| Morita, Hiroshi| Toh, Norihisa| Nakagawa, Koji| Yoshida, Masashi| Watanabe, Atsuyuki| Nishii, Nobuhiro| Miyoshi, Toru| Ito, Hiroshi|
Keywords Electrocardiography Fragmented QRS Hospitalization Hypertrophic cardiomyopathy Ventricular arrhythmia.
Published Date 2020-02-25
Publication Title Circulation Journal
Volume volume84
Issue issue3
Publisher The Japanese Circulation Society
Start Page 487
ISSN 1346-9843
NCID AA11591968
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © 2020 THE JAPANESE CIRCULATION SOCIETY
File Version publisher
PubMed ID 32037379
DOI 10.1253/circj.CJ-19-0968
Web of Science KeyUT 000516606400021
Related Url isVersionOf https://doi.org/10.1253/circj.CJ-19-0968
JaLCDOI 10.18926/AMO/31817
FullText URL fulltext.pdf
Author Ito, Hiroshi|
Abstract <p>For patients with acute myocardial infarction (MI), the immediate therapeutic goal is to establish the patency of the infarct-related artery. Prolonged myocardial ischemia, however, often breaks down the coronary microvasculature, and the flow to the infarct myocardium may be markedly reduced. This is called the no-reflow phenomenon. This phenomenon is important not solely because it correlates with infarct size but because it provides additional prognostic information. With recent advances in imaging modalities, the no-reflow phenomenon is observed more frequently than when clinical judgment alone is used. Patients with this phenomenon are associated with poor functional and clinical outcomes. Now, the no-reflow phenomenon can be a parameter with which to predict high-risk patients. The focus of reperfusion therapy has shifted toward the improvement of myocardial perfusion. The improvement of myocardial perfusion could promote the functional recovery of viable muscle and reduce infarct expansion, which is associated with favorable clinical outcomes. For this purpose, pharmacological interventions and catheter-based devices to retrieve embolic materials have been proposed. Advances in our understanding of the pathophysiology of microvascular dysfunction would aid the development of therapeutic strategies for its prevention and treatment.</p>
Keywords cardiac function coronary intervention microcirculation myocardial infarction reperfusion
Amo Type Review
Published Date 2009-08
Publication Title Acta Medica Okayama
Volume volume63
Issue issue4
Publisher Okayama University Medical School
Start Page 161
End Page 168
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
File Version publisher
Refereed True
PubMed ID 19727200
Web of Science KeyUT 000269228400001
FullText URL fulltext.pdf
Author Watanabe, Atsuyuki| Morita, Hiroshi| Kawada, Satoshi| Tachibana, Motomi| Morimoto, Yoshimasa| Ito, Hiroshi|
Keywords Asymptomatic Brugada syndrome Catheter ablation Epicardial mapping Open chest surgery
Published Date 2019-07-16
Publication Title HeartRhythm Case Reports
Volume volume5
Issue issue10
Publisher Elsevier
Start Page 501
End Page 504
ISSN 22140271
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © 2019 Heart Rhythm Society. Published by Elsevier Inc.
File Version publisher
PubMed ID 31700794
DOI 10.1016/j.hrcr.2019.07.003
Related Url isVersionOf https://doi.org/10.1016/j.hrcr.2019.07.003