Author Yashiro, Masato| Tsukahara, Hirokazu| Matsukawa, Akihiro| Yamada, Mutsuko| Fujii, Yosuke| Nagaoka, Yoshiharu| Tsuge, Mitsuru| Yamashita, Nobuko| Ito, Toshihiro| Yamada, Masao| Masutani, Hiroshi| Yodoi, Junji| Morishima, Tsuneo|
Published Date 2013-08-01
Publication Title 岡山医学会雑誌
Volume volume125
Issue issue2
Content Type Journal Article
Author Nakatsukasa, Yoko| Tsukahara, Hirokazu| Tabuchi, Kazuhisa| Tabuchi, Masako| Magami, Tomoko| Yamada, Mutsuko| Fujii, Yosuke| Yashiro, Masato| Tsuge, Mitsuru| Morishima, Tsuneo|
Published Date 2013-01-01
Publication Title Journal of Clinical Biochemistry and Nutrition
Volume volume52
Issue issue1
Content Type Journal Article
Author Ohno, Naoki| Ohtsuki, Shinichi| Kataoka, Koichi| Baba, Kenji| Okamoto, Yoshio| Kondo, Maiko| Sano, Shunji| Kasahara, Shingo| Honjo, Osami| Morishima, Tsuneo|
Published Date 2013-04
Publication Title Catheterization and Cardiovascular Interventions
Volume volume81
Issue issue5
Content Type Journal Article
Author Morishima, Tsuneo|
Published Date 2011-08-01
Publication Title 岡山医学会雑誌
Volume volume123
Issue issue2
Content Type Journal Article
JaLCDOI 10.18926/AMO/46630
FullText URL 65_3_185.pdf
Author Watanabe, Kumi| Okada, Ayumi| Okabe, Nobuyuki| Onishi, Masaru| Morishima, Tsuneo|
Abstract The purpose of this study was to investigate the psychological needs of children and adolescents with eating disorders (ED) directed toward their mothers. Patients with ED have low self-assertion and various abnormal eating behaviors. Therefore, mothers face difficulty in understanding their children's psychological needs, and the mother-child relationship is sometimes strained. We developed a One-Message Question (OMQ)-structured interview. The OMQ was easy to answer, and it helped the patients with ED. We examined the relationship between psychological needs and illness phase of the children and adolescents, and we discuss the viability of implementing the OMQ in clinical settings. The subjects were 23 patients and their parents. Their parents were just asked about the patients' background. The mean age of the patients was 15.8 years, and the average age of ED onset was 13.5 years. The EDs were anorexia nervosa (n=20) and bulimia nervosa (n=3). The phases of patients' illness were identified as anorexic (n=5), bulimic (n=7), chronic (n=3), and stable (n=8). All subjects provided specific responses to the OMQ-structured interview. Data analyses revealed the following seven categories of patients' psychological needs directed toward their mothers:attachment, cooperation in meeting their goals, longing for love, changing attitude toward family members, respect for self-reliance, expression of apology, and expression of appreciation. These findings suggested that the OMQ-structured interview may prove useful for mothers to understand their children's psychological needs and may encourage positive interactions as a foundation for future recovery.
Keywords family support mother-child relationships eating disorders in children and adolescents interview methods team approach
Amo Type Original Article
Published Date 2011-06
Publication Title Acta Medica Okayama
Volume volume65
Issue issue3
Publisher Okayama University Medical School
Start Page 185
End Page 192
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
Copyright Holders CopyrightⒸ 2011 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 21709716
Web of Science KeyUT 000292017500005
JaLCDOI 10.18926/AMO/32899
FullText URL fulltext.pdf
Author Hosogi, Mizuho| Okada, Ayumi| Yamanaka, Eriko| Ootyou, Keiko| Tsukamoto, Chiaki| Morishima, Tsuneo|
Abstract Self-esteem is the evaluative feelings one holds for oneself and the sense that one has essential worth. It is evaluated as the difference between the actual self and the ideal self. Healthy self-esteem supports psychological stability and positive social activity and is an essential element in the psychological development of children. The purpose of this study was to evaluate self-esteem in children with psychosomatic symptoms and elucidate a strategy for using such evaluations in therapy. We evaluated self-esteem in 56 patients at the Department of Pediatrics of Okayama University Hospital who were undergoing outpatient therapy for psychosomatic symptoms, using Pope's 5-scale test of self-esteem for children. We examined patient attributes, course of therapy, and social adjustment. Patients with low self-esteem on multiple scales at the first visit were all female, and these patients had a significantly higher frequency of family function problems, such as a family member with a psychiatric disorder, economic hardship, or experience of child abuse. Moreover, the prognosis for these patients was poor regardless of their social adjustment at the first visit.
Keywords self-esteem psychosomatic symptom family function child abuse 5-scale test of self-esteem
Amo Type Original Article
Published Date 2007-10
Publication Title Acta Medica Okayama
Volume volume61
Issue issue5
Publisher Okayama University Medical School
Start Page 271
End Page 281
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
File Version publisher
Refereed True
PubMed ID 17971844
Web of Science KeyUT 000250431700005
JaLCDOI 10.18926/AMO/32896
FullText URL fulltext.pdf
Author Okada, Ayumi| Tsukamoto, Chiaki| Hosogi, Mizuho| Yamanaka, Eriko| Watanabe, Kumi| Ootyou, Keiko| Morishima, Tsuneo|
Abstract Phagophobia is a disorder characterized by a conditioned excessive fear of eating and is initiated by an event such as vomiting or choking. During childhood, vomiting often occurs as a result of infection or overeating, and painful experiences bring about maladaptive eating behavior like food refusal. There have been few reports of phagophobia, and patients have sometimes been misdiagnosed with anorexia nervosa (AN). The objective of this study was to elucidate the psycho-pathology and current treatment of patients with phagophobia by analyzing case studies. We describe 6 cases with phagophobia. Patients with strong obsessions were refractory to treatment, indicating that evaluation of premorbid personality is crucial to the prognosis. It is important to classify this disorder according to psycho-pathology into "post-traumatic type" and "gain-from-illness type" to make a treatment plan. A solution focused approach is also effective for patients and their family. Paying close attention to these conditions and to the diagnostic concept referred as "hagophobia" is useful in achieving these aims.
Keywords phagophobia functional dysphagia eating disorder premorbid character solution focused approach
Amo Type Original Article
Published Date 2007-10
Publication Title Acta Medica Okayama
Volume volume61
Issue issue5
Publisher Okayama University Medical School
Start Page 261
End Page 269
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
File Version publisher
Refereed True
PubMed ID 17971843
Web of Science KeyUT 000250431700004
JaLCDOI 10.18926/AMO/31981
FullText URL fulltext.pdf
Author Ohtsuki, Shinnichi| Baba, Kenji| Kataoka, Kohichi| Ohno, Naoki| Okamoto, Yoshio| Ishino, Kozo| Kawada, Masaaki| Sano, Shunji| Sato, Shuhei| Morishima, Tsuneo|
Abstract <p>We investigated the usefulness of helical computed tomography(CT)in the morphological diagnosis of pulmonary vein stenosis, particularly that in infants and small children. In total, 20 helical CT examinations were performed in 10 post-operative cases of Total Anomalous Pulmonary Venous Drainage(TAPVD), 3 cases of single right ventricle, and 1 case of single left ventricle. In all cases, distinct morphological imaging was possible. Pulmonary vein stenosis could be categorized into three types: (1)stenosis from the anastomosis of the common pulmonary vein (CPV)-the left atrium (LA) to the peripheral pulmonary vein; (2) stenosis only at the anastomosis of CPV-LA; and (3) stenosis due to compression by nearby organs. Coronal views by multiplanar reconstruction (MPR) provided morphological information along the up-down direction of the body axis. Morphological diagnosis of pulmonary vein stenosis is important in deciding prognosis and therapeutic regimens, and helical CT was considered useful for such diagnosis in our 14 young patients.</p>
Keywords pulmonary vein stenosis helical CT
Amo Type Article
Published Date 2005-06
Publication Title Acta Medica Okayama
Volume volume59
Issue issue3
Publisher Okayama University Medical School
Start Page 93
End Page 98
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
File Version publisher
Refereed True
PubMed ID 16049562
Web of Science KeyUT 000230039100004
JaLCDOI 10.18926/AMO/31961
FullText URL fulltext.pdf
Author Yamashita, Nobuko| Kimura, Hiroshi| Morishima, Tsuneo|
Abstract <p>Epstein-Barr virus (EBV) is usually maintained in an asymptomatic and latent form by the host immune system, and primarily by EBV-specific cytotoxic T cells (CTLs). However, EBV has been linked to several refractory diseases such as EBV-associated hemophagocytic syndrome(EBV-AHS) and chronic active EBV infection (CAEBV). In these ectopic diseases, EBV infects T/NK cells, causing severe immunodeficiency with a very high EBV load. In recent years, the laboratory procedure to assess these types of EBV infections has been improved. In particular, real-time polymerase chain reaction (PCR) has been used to quantify the EBV load, and the MHC: peptide tetramer assay has been used to quantitate EBV-specific CTLs; these tests have been employed for the management of the illnesses associated with EBV infection. Here, we have reviewed the recent progress in the clinical application of these assays. The pathogenesis of EBV-infected T/NK cells, and the host immune response to infection, including the roles carried out by innate immunity and inflammatory cytokines, are likely to be revealed in the future.</p>
Keywords chronic active Epstein-Barr virus infection Epstein-Barr virus-associated hemophagocytic syndrome Real-time PCR tetramer
Amo Type Review
Published Date 2005-12
Publication Title Acta Medica Okayama
Volume volume59
Issue issue6
Publisher Okayama University Medical School
Start Page 239
End Page 246
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
File Version publisher
Refereed True
PubMed ID 16418766
Web of Science KeyUT 000234176600001
JaLCDOI 10.18926/AMO/30973
FullText URL fulltext.pdf
Author Maruyama, Hidehiko| Shinozuka, Masako| Kondoh, Yo-ichi| Akahori, Yo-ichiro| Matsuda, Miwa| Inoue, Seiji| Sumida, Yumi| Morishima, Tsuneo|
Abstract <p>Sick preterm infants often have thrombocytopenia at birth, and this is often associated with intrauterine growth restriction (IUGR), or birth weights less than the 10th percentile. The pathogenesis of the thrombocytopenia and its importance in IUGR are still unclear. We studied the characteristics of preterm IUGR infants with thrombocytopenia. Twenty-seven singleton Japanese preterm IUGR infants were born between January 2002 and June 2007 at Okayama University Hospital. Infants with malformation, chromosomal abnormalities, alloimmune thrombocytopenia, sepsis, and maternal aspirin ingestion were excluded. The infants were divided into group A (n&#65309;8), which had thrombocytopenia within 72h after birth, and group B (n&#65309;19), which did not. There were significant differences in birth weight, head circumference, umbilical artery (UA)-pulsatility index (PI), middle cerebral artery-PI, UA-pH, UA-pO2, and UA-pCO2. The infants in group A were smaller, had abnormal blood flow patterns, and were hypoxic at birth. We speculate that the infants with thrombocytopenia were more severely growth-restricted by chronic hypoxia. Thrombocytopenia is an important parameter for chronic hypoxia in the uterine.</p>
Keywords thrombocytopenia intrauterine growth restriction chronic hypoxia
Amo Type Original Article
Published Date 2008-10
Publication Title Acta Medica Okayama
Volume volume62
Issue issue5
Publisher Okayama University Medical School
Start Page 313
End Page 317
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
File Version publisher
Refereed True
PubMed ID 18985091
Web of Science KeyUT 000260391300005
JaLCDOI 10.18926/AMO/30740
FullText URL fulltext.pdf
Author Une, Tomoka| Yokoyama, Yuji| Ninomiya, Shinsuke| Shinozuka, Masako| Maruyama, Hidehiko| Morishima, Tsuneo|
Abstract Some marker chromosomes and chromosome rearrangements are difficult to identify using G-bands by Giemsa staining after trypsin treatment (G-banding) alone. Molecular cytogenetic techniques, such as spectral karyotyping (SKY) and fluorescence in situ hybridization (FISH), can help to detect chromosomal aberrations precisely. We analyzed the karyotypes in 6 cases of multiple congenital abnormalities and 1 case of spontaneous abortion (case 2). Three cases (cases 1, 6, and 7) had marker chromosomes, and 4 cases (cases 2-5) had chromosomal rearrangements. The karyotypes in cases 1, 2, and 3 were determined using FISH with probes based on the clinical findings and family histories. Spectral karyotyping (SKY) analysis in cases 4-7 showed that this method is useful and saves time. The combination of SKY and FISH analyses defi ned the range of the ring chromosome in case 7. We demonstrated that a combination of G-banding, FISH, and SKY can be applied effectively to the investigation of chromosomal rearrangement and to the detection of marker chromosome origins. We suggest the use of these methods for prenatal diagnosis, in which the inherent time limitations are particularly important.
Keywords spectral karyotyping fluorescence in situ hybridization molecular cytogenetics marker chromosome chromosome rearrangement
Amo Type Article
Published Date 2006-10
Publication Title Acta Medica Okayama
Volume volume60
Issue issue5
Publisher Okayama University Medical School
Start Page 279
End Page 287
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
File Version publisher
Refereed True
PubMed ID 17072374
Web of Science KeyUT 000241509000004