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ID 30402
JaLCDOI
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Author
Watanabe, Kazuhide
Eto, Koehi
Furuno, Katsushi
Mori, Takaaki
Kawasaki, Hiromu Kaken ID publons
Gomita, Yutaka
Abstract

The effect of cigarette smoke on organ weights, lipid peroxidation and plasma biochemical parameters was investigated in male Wistar rats. Daily exposure (for 20 min twice a day) to cigarette smoke for 27 days caused a significant decrease in liver weight and a significant increase in lung weight. The smoke-exposure group showed increased lipid peroxidation in the liver, but not in the lung. In the smoke-exposure group, the GOT, gamma-GTP, total bilirubin and LDH values were significantly higher than those in the control group, while the plasma glucose value was significantly lower. These results suggest that cigarette smoking might induce liver injury by enhancing lipid peroxidation.

Keywords
cigarette smoking
lipid peroxidation
liver function
rats
Amo Type
Article
Published Date
1995-10
Publication Title
Acta Medica Okayama
Volume
volume49
Issue
issue5
Publisher
Okayama University Medical School
Start Page
271
End Page
274
ISSN
0386-300X
NCID
AA00508441
Content Type
Journal Article
language
英語
File Version
publisher
Refereed
True
PubMed ID
Web of Science KeyUT