Author Makihara, Seiichiro| Okano, Mitsuhiro|
Published Date 2015-04-01
Publication Title 岡山医学会雑誌
Volume volume127
Issue issue1
Content Type Journal Article
Title Alternative Sublingual Immunotherapy
FullText URL 126_165.pdf
Author Okano, Mitsuhiro|
Publication Title 岡山医学会雑誌
Published Date 2014-08-01
Volume volume126
Issue issue2
Start Page 165
End Page 166
ISSN 0030-1558
language 日本語
Copyright Holders Copyright (c) 2014 岡山医学会
File Version publisher
DOI 10.4044/joma.126.165
NAID 130004685270
Author Higaki, T| Okano, M| Fujiwara, T| Makihara, S| Kariya, S| Noda, Y| Haruna, T| Nishizaki, K|
Published Date 2012-08
Publication Title Clinical and Experimental Allergy
Volume volume42
Issue issue8
Content Type Journal Article
JaLCDOI 10.18926/AMO/31594
FullText URL fulltext.pdf
Author Nishioka, Keiko| Meguro, Tadamichi| Okano, Mitsuhiro| Masuda, Yu| Saito, Chisato| Yasumitsu, Eiji|
Abstract <p>Fifteen patients with Japanese cedar pollenosis were examined for lower airway function. Flow-volume patterns obtained from flow-volume and volume-time curves during the pollen season (March) and outside of the pollen season (June) were evaluated. In a previous report we classified maximal expiratory flow-volume (MEFV) curves in five patterns from A to E. In the present study, the patterns did not vary between the two periods except in one patient. Eleven patients out of 15 showed type E patterns, in which the flow-volume curve was concave along its entire course. In most of the patients with severe or moderate symptoms of allergic rhinitis only during the pollen season, the curve shifted to the right, but the parameters of the curves did not increase significantly outside of season. These findings suggest that patients with Japanese cedar pollenosis suffer from continuous latent peripheral airway obstruction. Extremely slight changes in the flow rate were detected by comparing the curves obtained during the two periods.</p>
Keywords pulmonary function test pollenosis pollinosis maximal expiratory flow-volume curve flowvolume pattern
Amo Type Article
Published Date 1993-06
Publication Title Acta Medica Okayama
Volume volume47
Issue issue3
Publisher Okayama University Medical School
Start Page 151
End Page 156
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
File Version publisher
Refereed True
PubMed ID 8379343
Web of Sience KeyUT A1993LL12400003
JaLCDOI 10.18926/AMO/31119
FullText URL fulltext.pdf
Author Nishioka, Keiko| Saito, Chisato| Nagano, Toshiaki| Okano, Mitsuhiro| Nakagawa, Fumio| Nishioka, Satoko| Masuda, Yu| Ono, Toshiro|
Abstract <p>To determine the allergens of mite allergic rhinitis, we studied 31 patients with mite allergic rhinitis by skin tests and nasal provocation tests (15 for skin and 16 for nasal tests) using 6 fractions of Dermatophagoides pteronyssinus (Dp) extract differing in molecular weights (15, 25, 32, 53, 95 and 190 kDMW). In skin testing, patients showed intense positive reactions to the fractions of 15, 25, 32, 95 and 190 kDMW, among which the most patients showed positive reactions to the fractions of 15 and 25 kDMW. Significant differences were found in patients' positive reactivity among each fraction and between low (15 and 25 kD) and high (95 and 190 kD) molecular weight fractions as well. In nasal provocation tests, patients showed intense positive reactions to the fractions of 15, 32, 53 and 95 kDMW, especially to the fractions of 15 and 95 kDMW. Furthermore, the insidence of positive reactions to the 15 kDMW fraction was significantly higher than that to any other fraction in the skin tests (P &#60; 0.05). From these results, the low molecular weight fraction, 15 kDMW, is considered to be the main allergen of this mite and the high molecular weight fractions, 95 and 190 kDMW, may also be considered to be allergens of this mite.</p>
Keywords mite allergen skin test nasal provoration test allergen rhinitis
Amo Type Article
Published Date 1994-10
Publication Title Acta Medica Okayama
Volume volume48
Issue issue5
Publisher Okayama University Medical School
Start Page 279
End Page 282
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
File Version publisher
Refereed True
PubMed ID 7863799
Web of Sience KeyUT A1994PP23600008
JaLCDOI 10.18926/AMO/31114
FullText URL fulltext.pdf
Author Nishioka, Keiko| Saito, Chisato| Nagano, Toshiaki| Okano, Mitsuhiro| Nakagawa, Fumio| Nishioka, Satoko| Masuda, Yu| Ono, Toshiro|
Abstract <p>To determine the allergens of mite allergic rhinitis, we studied 31 patients with mite allergic rhinitis by skin tests and nasal provocation tests (15 for skin and 16 for nasal tests) using 6 fractions of Dermatophagoides pteronyssinus (Dp) extract differing in molecular weights (15, 25, 32, 53, 95 and 190 kDMW). In skin testing, patients showed intense positive reactions to the fractions of 15, 25, 32, 95 and 190 kDMW, among which the most patients showed positive reactions to the fractions of 15 and 25 kDMW. Significant differences were found in patients' positive reactivity among each fraction and between low (15 and 25 kD) and high (95 and 190 kD) molecular weight fractions as well. In nasal provocation tests, patients showed intense positive reactions to the fractions of 15, 32, 53 and 95 kDMW, especially to the fractions of 15 and 95 kDMW. Furthermore, the insidence of positive reactions to the 15 kDMW fraction was significantly higher than that to any other fraction in the skin tests (P &#60; 0.05). From these results, the low molecular weight fraction, 15 kDMW, is considered to be the main allergen of this mite and the high molecular weight fractions, 95 and 190 kDMW, may also be considered to be allergens of this mite.</p>
Keywords mite allergen skin test nasal provoration test allergen rhinitis
Amo Type Article
Published Date 1994-10
Publication Title Acta Medica Okayama
Volume volume48
Issue issue5
Publisher Okayama University Medical School
Start Page 279
End Page 282
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
File Version publisher
Refereed True
PubMed ID 7863799
Web of Sience KeyUT A1994PP23600008
Author Nomiya, Rie| Okano, Mitsuhiro| Fujiwara, Tazuko| Nishizaki, Kazunori|
Published Date 2009-08-03
Publication Title 岡山医学会雑誌
Volume volume121
Issue issue2
Content Type Journal Article
Author Okano, Mitsuhiro|
Published Date 2008-08-01
Publication Title 岡山医学会雑誌
Volume volume120
Issue issue2
Content Type Journal Article
Author 岡野 光博|
Published Date 1993-03-31
Publication Title
Content Type Thesis or Dissertation