Author Tomoda, Takeshi| Kato, Hironari| Miyamoto, Kazuya| Matsumi, Akihiro| Ueta, Eijiro| Fujii, Yuuki| Saragai, Yousuke| Yamazaki, Tatsuhiro| Uchida, Daisuke| Matsumoto, Kazuyuki| Horiguchi, Shigeru| Tsutsumi, Koichiro| Okada, Hiroyuki|
Keywords diclofenac low dose post‐ERCP pancreatitis
Note This is the peer reviewed version of the following article: Takeshi Tomoda et. al. Efficacy of low dose rectal diclofenac for preventing post‐endoscopic retrograde cholangiopancreatography pancreatitis: Propensity score‐matched analysis. Digestive Endoscopy, which has been published in final form at https://doi.org/10.1111/den.13828. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.</br> This fulltext is available in Sep. 2021.|
Published Date 2020-09-02
Publication Title Digestive Endoscopy
Publisher Wiley
ISSN 0915-5635
NCID AA10907137
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
File Version author
PubMed ID 32881078
DOI 10.1111/den.13828
Web of Science KeyUT 000577757600001
Related Url isVersionOf https://doi.org/10.1111/den.13828
FullText URL fulltext.pdf
Author Miyamoto, Kazuya| Matsumoto, Kazuyuki| Kato, Hironari| Yoshida, Ryuichi| Umeda, Yuzo| Inoue, Hirohumi| Tanaka, Takehiro| Matsumi, Akihiro| Saragai, Yosuke| Fujii, Yuki| Yamazaki, Tatsuhiro| Uchida, Daisuke| Tomoda, Takeshi| Horiguchi, Shigeru| Yagi, Takahito| Okada, Hiroyuki|
Keywords IPMN PJC LBC BD SurePath
Published Date 2020-09-29
Publication Title BMC Gastroenterology
Volume volume20
Issue issue1
Publisher BMC
Start Page 319
ISSN 1471-230X
NCID AA12034934
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s). 2020
File Version publisher
PubMed ID 32993498
DOI 10.1186/s12876-020-01465-y
Web of Science KeyUT 000576989100004
Related Url isVersionOf https://doi.org/10.1186/s12876-020-01465-y
FullText URL fulltext.pdf
Author Matsumoto, Kazuyuki| Kato, Hironari| Horiguchi, Shigeru| Tomoda, Takeshi| Matsumi, Akihiro| Ishihara, Yuki| Saragai, Yosuke| Takada, Saimon| Muro, Shinichiro| Uchida, Daisuke| Okada, Hiroyuki|
Keywords Endoscopic ultrasound-guided fine needle aspiration Pancreaticobiliary cancer Neoplasm recurrence
Published Date 2020
Publication Title Gut and Liver
Volume volume14
Issue issue5
Publisher Gut and Liver
Start Page 652
End Page 658
ISSN 1976-2283
NCID AA12329814
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
File Version publisher
PubMed ID 31818050
DOI 10.5009/gnl19200
Web of Science KeyUT 000569359000016
Related Url isVersionOf https://doi.org/10.5009/gnl19200
JaLCDOI 10.18926/AMO/60364
FullText URL 74_4_275.pdf
Author Muro, Taiko| Nakamura, Shinichiro| Takaki, Akinobu| Onishi, Hideki| Wada, Nozomu| Yasunaka, Tetsuya| Uchida, Daisuke| Oyama, Atsushi| Adachi, Takuya| Shiraha, Hidenori| Okada, Hiroyuki|
Abstract Radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC) is a promising method for controlling tumors, although it does not entirely eliminate recurrence. Oxidative stress is associated with the progression of hepatocarcinogenesis, while also acting as an anticancer response. The objective of the present study was to investigate the factors influencing post-RFA outcomes. We recruited 235 newly diagnosed HCC patients who received RFA for single tumors. The patients with recurrence were sub-grouped into early and segmental recurrence groups. The characteristics of the sub-grouped patients were evaluated, including by measuring oxidative stress marker reactive oxygen metabolites and antioxidant marker OXY-adsorbent tests. The factors associated with poor survival were a high Child-Pugh score and early recurrence within 2 years in the same segment. The patients who experienced recurrence within 2 years in the same segment showed a larger tumor diameter than did others. According to a multivariate analysis, the OXY values were also significantly low in these patients. In conclusion, maintaining the antioxidant reservoir function with a high OXY value might be necessary to prevent early recurrence within the RFA-treated segment.
Keywords oxidative stress hepatocellular carcinoma recurrence, radiofrequency ablation
Amo Type Original Article
Published Date 2020-08
Publication Title Acta Medica Okayama
Volume volume74
Issue issue4
Publisher Okayama University Medical School
Start Page 275
End Page 283
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
Copyright Holders CopyrightⒸ 2020 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 32843758
Web of Science KeyUT 000562508700002
NAID 120006880203
FullText URL fulltext.pdf
Author Uchida, Daisuke| Takaki, Akinobu| Oyama, Atsushi| Adachi, Takuya| Wada, Nozomu| Onishi, Hideki| Okada, Hiroyuki|
Keywords oxidative stress chronic hepatitis hepatocellular carcinoma
Published Date 2020-05-28
Publication Title Nutrients
Volume volume12
Issue issue6
Publisher MDPI
Start Page 1576
ISSN 2072-6643
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © 2020 by the authors.
File Version publisher
PubMed ID 32481552
DOI 10.3390/nu12061576
Web of Science KeyUT 000554005200001
Related Url isVersionOf https://doi.org/10.3390/nu12061576
JaLCDOI 10.18926/AMO/59957
FullText URL 74_3_237.pdf
Author Oyama, Atsushi| Uchida, Daisuke| Shiraha, Hidenori| Sawahara, Hiroaki| Kato, Ryo| Iwamuro, Masaya| Horiguchi, Shigeru| Okada, Hiroyuki|
Abstract The physiological role of the reduced expression of immortalized cells (REIC)/Dickkopf-3 (Dkk-3) protein in patients with hepatocellular carcinoma (HCC) remains unclear. In this study, we evaluated the effect of the REIC/Dkk-3 protein on HCC cell proliferation and assessed the relationship between the serum REIC/Dkk-3 protein level and the prognosis in patients with HCC. We evaluated the REIC/Dkk-3 protein-induced anticancer effects on Huh7 and Hep3B cells (HCC cell lines) in the presence of peripheral blood mononuclear cells (PBMCs), and found that combination treatment with REIC/Dkk-3 protein and PBMCs reduced the proliferation of HCC cells (Hep3B: 82.0%±16.3%; Huh7: 72.6%±9.1%). We also studied 194 HCC patients who underwent primary liver resection or primary radiofrequency ablation from 2008 to 2017. Serum REIC/Dkk-3 protein levels were measured by an enzyme-linked immunosorbent assay and compared to the prognostic data. The 3-year disease-free survival of the REIC/Dkk-3 high group was significantly higher than that in the REIC/Dkk-3 low group. In conclusion, this is the first study investigating the relationship between HCC patient survival and serum REIC/Dkk-3 protein levels in a large population. Based on the results, the serum REIC/Dkk-3 protein level should be considered a new prognostic marker for patients with HCC.
Keywords enzyme-linked immunosorbent assay liver resection primary radiofrequency ablation Huh7 Hep3B
Amo Type Original Article
Published Date 2020-06
Publication Title Acta Medica Okayama
Volume volume74
Issue issue3
Publisher Okayama University Medical School
Start Page 237
End Page 243
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
Copyright Holders CopyrightⒸ 2020 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 32577022
Web of Science KeyUT 000543363400007
NAID 120006862798
Author Tomoda, Takeshi | Kato, Hironari| Miyamoto, Kazuya| Matsumi, Akihiro| Ueta, Eijiro| Fujii, Yuuki| Saragai, Yousuke| Yamazaki, Tatsuhiro| Uchida, Daisuke| Matsumoto, Kazuyuki| Horiguchi, Shigeru| Tsutsumi, Koichiro| Okada, Hiroyuki|
Note Correction to: Surgical Endoscopy https://doi.org/10.1007/s00464-020-07385-y </br>This fulltext is available in Feb. 2021.|
Published Date 2020-02-06
Publication Title Surgical Endoscopy
Publisher Springer
ISSN 09302794
NCID AA10750363
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
File Version author
PubMed ID 32030547
DOI 10.1007/s00464-020-07399-6
Web of Science KeyUT 000515963500002
Related Url isVersionOf https://doi.org/10.1007/s00464-020-07399-6
FullText URL fulltext.pdf
Author Uchida, Daisuke| Kato, Hironari| Matsumoto, Kazuyuki| Ishihara, Yuki| Matsumi, Akihiro| Saragai, Yosuke| Takada, Saimon| Yabe, Shuntaro| Muro, Shinichiro| Tomoda, Takeshi| Horiguchi, Shigeru| Okada, Hiroyuki|
Keywords Endoscopic ultrasound Diagnostic screening program Pancreatic diseases Biliary tract diseases
Published Date 2019-12-18
Publication Title BMC Gastroenterology
Volume volume19
Issue issue1
Publisher BMC
Start Page 220
ISSN 1471-230X
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s). 2019
File Version publisher
PubMed ID 31852458
DOI 10.1186/s12876-019-1141-7
Web of Science KeyUT 000510482800002
Related Url isVersionOf https://doi.org/10.1186/s12876-019-1141-7